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• W2063284856 abstract "In recent years ecological research has focused on the relevance of antioxidants and oxidative stress in the evolution of life-history strategies and physiological trade-off in birds. Some studies sought to evaluate whether a consequence of immune response is oxidative stress. In a meta-analysis of 16 studies of ten species of birds including 49 estimates of effect size from experimental studies, we show that induction of an immune response in a diverse group of bird species may determine oxidative stress (variance explained: 4.1%), but, most notably, may determine changes in oxidative stress markers (variance explained: 15.0%). These conclusions were robust to control for sampling effort and publication bias. Finally, this finding suggests that (1) oxidative stress may be a physiological cost associated with the immune response and (2) an important role of antioxidants in birds is to control the potentially negative effects of such oxidative stress to prevent immuno-pathological damage to host tissues." @default.
• W2063284856 created "2016-06-24" @default.
• W2063284856 creator A5039382493 @default.
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• W2063284856 date "2009-07-01" @default.
• W2063284856 modified "2023-09-30" @default.
• W2063284856 title "Does immune response cause oxidative stress in birds? A meta-analysis" @default.
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• W2063284856 doi "https://doi.org/10.1016/j.cbpa.2009.03.010" @default.
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