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- W2063300935 abstract "The definition and clinical significance of vertebral artery hypoplasia (VAH) remain inconclusive. VAH has been proposed as a predisposing factor of posterior circulation ischemic stroke. The aim of this study was to determine a best cut-off diameter of vertebral artery (VA) for VAH and to investigate if unilateral VAH is associated with a decrease in net vertebral flow volume. Retrospective data of 1000 presumably healthy subjects free of cerebrovascular disease or apparent carotid atherosclerosis were analysed. We found that a VA diameter ≤2.5 mm is an ideal value to define VAH. The flow volume of the identified hypoplastic VA was remarkably low and the contralateral VA had only a slightly increased compensatory flow volume. The net VA flow volumes remained significantly and markedly lower in subjects with unilateral VAH (140.7±46.2 mL/min) than those in subjects without VAH (190.1±54.5 mL/min, p<0.001). Flow volume insufficiency of VA (defined as a net VA flow volume less than 100 mL/min) occurred more frequently in individuals with VAH than in those without VAH (22.1% vs. 2.4%, p<0.001). Our study suggested that asymptomatic subjects with VAH had a significantly lower net VA flow volume and a higher frequency of VA flow insufficiency than the control group. (E-mail: [email protected] )" @default.
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- W2063300935 date "2010-01-01" @default.
- W2063300935 modified "2023-10-16" @default.
- W2063300935 title "Vertebral Artery Hypoplasia is Associated With A Decrease in Net Vertebral Flow Volume" @default.
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- W2063300935 doi "https://doi.org/10.1016/j.ultrasmedbio.2009.08.012" @default.
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