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• W2063308932 abstract "Objectives. In the U.S., the total number of antimicrobials prescribed in ambulatory care declined between 1989 and 2000; however, antimicrobial resistance increased among many pathogens. We evaluated antimicrobial prescribing patterns from 1992 to 2004 in Alaska Native/American Indian (AI/AN) persons <18 years old, residing in the Anchorage region who received care through the AI/AN health system.Study design. Retrospective study based on medical records.Methods. Medical records were used to obtain data on oral antibiotics prescribed for ambulatory and emergency-room visits. Antimicrobial prescribing rates were calculated per population and per ambulatory-clinic visit.Results. The total number of antimicrobial courses prescribed increased 94% from 4,929 (1992) to 9,561 (2004). However, the total number of ambulatory-clinic visits also increased (79%) from 49,008 (1992) to 87,486 (2004), while the population of AI/AN persons <18 in Anchorage region rose 14%. The population-based rate of antimicrobial prescriptions (per 1,000 persons) rose from 309 (1992) to 524 (2004) (p<0.001). The visit-based annual rate (per 1,000 visits) remained stable from 101 (1992) to 109 (2004) (p=0.651). Overall, visit-based prescription rates in AI/AN persons were lower than previously reported among children in the U.S. (range 250–340). Penicillins comprised >50% of antimicrobials prescribed from 1992 to 2004. Visit-based prescribing rates from 1992 to 2004 changed: penicillin, +27% (p=0.210); cephalosporins, +33% (p=0.023); trimethoprim-sulfamethexazole, −48% (p<0.001).Conclusions. Visit-based antimicrobial prescribing rates in the Anchorage region for AI/AN children receiving care in the AI/AN health system have been stable over a 13-year period. Although a trend in decreased antibiotic prescribing has been seen in the general U.S. population, visit-based prescribing rates in the Anchorage region for AI/AN children have remained below those in previous studies in the U.S." @default.
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• W2063308932 date "2009-09-01" @default.
• W2063308932 modified "2023-10-14" @default.
• W2063308932 title "Trends in antimicrobial prescribing rates for Alaska native and American Indian persons <18 years of age residing in the anchorage region" @default.
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• W2063308932 doi "https://doi.org/10.3402/ijch.v68i4.17363" @default.
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