FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2063312585> ?p ?o ?g. }

• W2063312585 endingPage "196" @default.
• W2063312585 startingPage "186" @default.
• W2063312585 abstract "Through metabolic imprinting mechanisms a number of bioactive molecules including polyunsaturated fatty acids affect brain functions in the developmental age and longer-lasting beneficial effects are expected. In this study pregnant rats were offered diets either containing no docosahexaenoic acid (DHA) and arachidonic acid (AA) (Placebo diet) or an excess amount of these long chain polyunsaturated fatty acids (LC-PUFA) (Supplement diet) up to the time of weaning. Bilateral N-methyl-D-aspartate (NMDA) induced neurodegeneration in the entorhinal cortex of offspring in the age of 4 months was used as a tool to investigate the neuroprotective property of the developmentally supplemented DHA and AA treatments. Hippocampus-dependent spatial learning was measured in Morris water maze and the extent of neuronal lesion in the injected brain area was evaluated. Under baseline condition, in intact or sham-lesioned rats, the Morris water maze performance was superior in the supplemented group compared to the placebo controls. NMDA-lesion in the entorhinal cortex area decreased spatial learning in the supplement-treated rats while insignificantly diminished it in the placebo controls. The same supplementation attenuated the lesion size induced by the NMDA injection into the entorhinal and ventral hippocampal areas. We concluded that LC-PUFA supplementation during fetal and early postnatal development results in long-term enhancement of spatial learning ability of the offspring and offers resistance against excitotoxic brain lesion which lasts up to the adult age." @default.
• W2063312585 created "2016-06-24" @default.
• W2063312585 creator A5063259248 @default.
• W2063312585 creator A5067766820 @default.
• W2063312585 creator A5078845750 @default.
• W2063312585 creator A5087863283 @default.
• W2063312585 creator A5090808653 @default.
• W2063312585 date "2013-06-01" @default.
• W2063312585 modified "2023-09-25" @default.
• W2063312585 title "Developmental docosahexaenoic and arachidonic acid supplementation improves adult learning and increases resistance against excitotoxicity in the brain" @default.
• W2063312585 cites W1574545748 @default.
• W2063312585 cites W1601004171 @default.
• W2063312585 cites W1854167840 @default.
• W2063312585 cites W1902475818 @default.
• W2063312585 cites W1913763137 @default.
• W2063312585 cites W1969116800 @default.
• W2063312585 cites W1982549915 @default.
• W2063312585 cites W1990926307 @default.
• W2063312585 cites W2003169732 @default.
• W2063312585 cites W2010313286 @default.
• W2063312585 cites W2013320345 @default.
• W2063312585 cites W2016738931 @default.
• W2063312585 cites W2022222324 @default.
• W2063312585 cites W2050850638 @default.
• W2063312585 cites W2054843695 @default.
• W2063312585 cites W2060688692 @default.
• W2063312585 cites W2069349498 @default.
• W2063312585 cites W2074194961 @default.
• W2063312585 cites W2084249153 @default.
• W2063312585 cites W2096601431 @default.
• W2063312585 cites W2098338770 @default.
• W2063312585 cites W2098645049 @default.
• W2063312585 cites W2099363307 @default.
• W2063312585 cites W2101768694 @default.
• W2063312585 cites W2103279359 @default.
• W2063312585 cites W2111443842 @default.
• W2063312585 cites W2119810192 @default.
• W2063312585 cites W2121593446 @default.
• W2063312585 cites W2130852003 @default.
• W2063312585 cites W2132860088 @default.
• W2063312585 cites W2134398800 @default.
• W2063312585 cites W2134907293 @default.
• W2063312585 cites W2137720554 @default.
• W2063312585 cites W2138380366 @default.
• W2063312585 cites W2139699171 @default.
• W2063312585 cites W2142915816 @default.
• W2063312585 cites W2165295002 @default.
• W2063312585 cites W2169473035 @default.
• W2063312585 cites W4239727071 @default.
• W2063312585 cites W4376542647 @default.
• W2063312585 cites W4377077114 @default.
• W2063312585 doi "https://doi.org/10.1556/aphysiol.100.2013.005" @default.
• W2063312585 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23524180" @default.
• W2063312585 hasPublicationYear "2013" @default.
• W2063312585 type Work @default.
• W2063312585 sameAs 2063312585 @default.
• W2063312585 citedByCount "5" @default.
• W2063312585 countsByYear W20633125852015 @default.
• W2063312585 countsByYear W20633125852018 @default.
• W2063312585 countsByYear W20633125852020 @default.
• W2063312585 countsByYear W20633125852023 @default.
• W2063312585 crossrefType "journal-article" @default.
• W2063312585 hasAuthorship W2063312585A5063259248 @default.
• W2063312585 hasAuthorship W2063312585A5067766820 @default.
• W2063312585 hasAuthorship W2063312585A5078845750 @default.
• W2063312585 hasAuthorship W2063312585A5087863283 @default.
• W2063312585 hasAuthorship W2063312585A5090808653 @default.
• W2063312585 hasConcept C112672928 @default.
• W2063312585 hasConcept C126322002 @default.
• W2063312585 hasConcept C134018914 @default.
• W2063312585 hasConcept C142724271 @default.
• W2063312585 hasConcept C148762608 @default.
• W2063312585 hasConcept C170493617 @default.
• W2063312585 hasConcept C181199279 @default.
• W2063312585 hasConcept C19038510 @default.
• W2063312585 hasConcept C25498285 @default.
• W2063312585 hasConcept C2777171753 @default.
• W2063312585 hasConcept C2778078955 @default.
• W2063312585 hasConcept C2779234561 @default.
• W2063312585 hasConcept C2780655333 @default.
• W2063312585 hasConcept C2780715579 @default.
• W2063312585 hasConcept C2781012912 @default.
• W2063312585 hasConcept C2781156865 @default.
• W2063312585 hasConcept C2781161787 @default.
• W2063312585 hasConcept C44752575 @default.
• W2063312585 hasConcept C543025807 @default.
• W2063312585 hasConcept C54355233 @default.
• W2063312585 hasConcept C55493867 @default.
• W2063312585 hasConcept C67018056 @default.
• W2063312585 hasConcept C71924100 @default.
• W2063312585 hasConcept C86803240 @default.
• W2063312585 hasConceptScore W2063312585C112672928 @default.
• W2063312585 hasConceptScore W2063312585C126322002 @default.
• W2063312585 hasConceptScore W2063312585C134018914 @default.
• W2063312585 hasConceptScore W2063312585C142724271 @default.
• W2063312585 hasConceptScore W2063312585C148762608 @default.
• W2063312585 hasConceptScore W2063312585C170493617 @default.
• W2063312585 hasConceptScore W2063312585C181199279 @default.

• next