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• W2063325412 abstract "In 1901, Opie¹described acute hemorrhagic and necrotizing pancreatitis. He observed a stone impacted in the ampulla of Vater at autopsy in a case of acute hemorrhagic pancreatitis. The pancreatic duct was bile-stained. He demonstrated that, with pressure on the gall bladder, bile could be forced into the duct of Wirsung. He postulated the common-channel theory as a cause of the disease. His thesis was based upon observations made in 100 human bile- and pancreatic-duct dissections. He found that reflux from the bile duct into the pancreatic duct was possible in 30% of cases, when a stone obstructed the termination of the ducts. Prior to Opie's report, Claude Bernard²had demonstrated that bile and olive oil injected up the pancreatic ducts of experimental animals produced acute pancreatitis. Later reports of Opie,³in 1903, started a wave of experimental and clinical investigations into the possibility of bile reflux" @default.
• W2063325412 created "2016-06-24" @default.
• W2063325412 creator A5034201795 @default.
• W2063325412 creator A5050472684 @default.
• W2063325412 date "1956-06-01" @default.
• W2063325412 modified "2023-09-27" @default.
• W2063325412 title "Acute Hemorrhagic Pancreatitis Following Biliary-Tract Surgical Procedures" @default.
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• W2063325412 doi "https://doi.org/10.1001/archsurg.1956.01270240043007" @default.
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