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• W2063326536 abstract "Abstract The effects of olive oil (OO)- and high-oleic sunflower oil (HOSO)-enriched diets on erythrocyte membrane cholesterol distribution (by means of cholesterol oxidation after continuous cholesterol oxidase treatment) and Na + Li + countertransport activity in control subjects and patients with untreated essential hypertension (with or without concomitant hypercholesterolemia) have been examined. The participants were 12 normotensive and sixteen hypertensive women who consumed in randomized order the two monosaturated fatty acid (MUFA) diets over 4-week periods separated by a 4-week washout period. The half-times for cholesterol oxidation were significantly higher in hypertensive women, ranging from an increase of 38 to 57% in the normo-(20.6 ± 2.8 min; P P + Li + countertransport was found to be significantly higher in hypertensive women, ranging the increase from 22 to 57% in the normo-(0.314 ± 0.043 mmol × [h × liter cell] −1 ; P −1 ; P + Li + countertransport in erythrocyte of hypertensive patients. This action of OO also indicates that alterations in membrane cholesterol distribution may be relevants for the pathogenesis of hypertension. The effects, however, cannot be exclusively attributed to the content of MUFAs (mainly oleic acid) in the diet, as HOSO was unable to induce favorable changes." @default.
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• W2063326536 date "1997-04-01" @default.
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• W2063326536 title "Olive oil normalizes the altered distribution of membrane cholesterol and Na+Li+ countertransport activity in erythrocyte of hypertensive patients" @default.
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• W2063326536 doi "https://doi.org/10.1016/s0955-2863(97)00005-3" @default.
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