FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2063341874> ?p ?o ?g. }

• W2063341874 endingPage "S296" @default.
• W2063341874 startingPage "S291" @default.
• W2063341874 abstract "The rising incidence and prevalence of chronic kidney disease (CKD) (glomerular filtration rate <60 mL/min per 1.73 m2) is a major public health concern (U.S. Renal Data System 2010, http://www.usrds.org). Hypertension is the second leading cause of end-stage renal disease (ESRD) in the U.S. and is also a major contributor to diabetic renal disease, which is the leading cause of CKD and ESRD (U.S. Renal Data System 2010). The diabetes-related ESRD annual incidence rate has been decreasing since 1996, suggesting that the net increase in diabetes-related ESRD may be secondary to the documented pandemic of type 2 diabetes (1,2).In the general population, CKD predicts death and cardiovascular disease (CVD) events, independently of traditional cardiovascular risk factors such as age, sex, prior CVD, diabetes, hypertension, dyslipidemia, and proteinuria (3). CKD in patients with type 2 diabetes is independently associated with an ∼8–10% annual absolute risk for death and CVD (4). The majority of patients with CKD will die of a CVD event before they reach end-stage renal failure and dialysis treatment (5), and an estimated glomerular filtration rate <60 mL/min is now classified as a major independent risk factor for CVD.Endothelial dysfunction has been implicated as a potential major mechanism for renal chronic microvascular complications both in diabetic and nondiabetic patients with albuminuria. There is a general assumption of a final common biological pathway that results in diabetic kidney disease and renal failure. As shown in Fig. 1, hyperglycemia and hypertension interact at the glomerulus, resulting in glomerular hypertension and, as a consequence, proteinuria, glomerular and interstitial tissue fibrosis (6), progressive decline in glomerular filtration rate, and finally renal failure.Figure 1 Principal mechanisms of diabetic glomerulopathy. Hyperglycemia and hypertension interact at the glomerulus, resulting in glomerular hypertension, progressive glomerular and interstitial tissue fibrosis, and decline …" @default.
• W2063341874 created "2016-06-24" @default.
• W2063341874 creator A5032861135 @default.
• W2063341874 creator A5059051905 @default.
• W2063341874 date "2011-04-22" @default.
• W2063341874 modified "2023-09-23" @default.
• W2063341874 title "Endothelial Factors and Diabetic Nephropathy" @default.
• W2063341874 cites W1566059459 @default.
• W2063341874 cites W1971452427 @default.
• W2063341874 cites W1973436528 @default.
• W2063341874 cites W1976221241 @default.
• W2063341874 cites W1979237115 @default.
• W2063341874 cites W1985222413 @default.
• W2063341874 cites W1991399924 @default.
• W2063341874 cites W2004083442 @default.
• W2063341874 cites W2005502601 @default.
• W2063341874 cites W2010413021 @default.
• W2063341874 cites W2020999059 @default.
• W2063341874 cites W2021162593 @default.
• W2063341874 cites W2028031291 @default.
• W2063341874 cites W2030652589 @default.
• W2063341874 cites W2039537505 @default.
• W2063341874 cites W2042318705 @default.
• W2063341874 cites W2044437167 @default.
• W2063341874 cites W2045666817 @default.
• W2063341874 cites W2046256807 @default.
• W2063341874 cites W2046303127 @default.
• W2063341874 cites W2050071967 @default.
• W2063341874 cites W2058323492 @default.
• W2063341874 cites W2066834504 @default.
• W2063341874 cites W2076422702 @default.
• W2063341874 cites W2084062068 @default.
• W2063341874 cites W2097417946 @default.
• W2063341874 cites W2100454247 @default.
• W2063341874 cites W2101337813 @default.
• W2063341874 cites W2107432878 @default.
• W2063341874 cites W2117301812 @default.
• W2063341874 cites W2120953129 @default.
• W2063341874 cites W2121863058 @default.
• W2063341874 cites W2123097597 @default.
• W2063341874 cites W2123310055 @default.
• W2063341874 cites W2128545033 @default.
• W2063341874 cites W2130771083 @default.
• W2063341874 cites W2131801871 @default.
• W2063341874 cites W2132418620 @default.
• W2063341874 cites W2133182110 @default.
• W2063341874 cites W2136131782 @default.
• W2063341874 cites W2138631477 @default.
• W2063341874 cites W2139359754 @default.
• W2063341874 cites W2142041241 @default.
• W2063341874 cites W2145632027 @default.
• W2063341874 cites W2145785082 @default.
• W2063341874 cites W2146867458 @default.
• W2063341874 cites W2149109717 @default.
• W2063341874 cites W2153816764 @default.
• W2063341874 cites W2153946946 @default.
• W2063341874 cites W2167634088 @default.
• W2063341874 cites W2169076924 @default.
• W2063341874 cites W2169712470 @default.
• W2063341874 cites W2170950091 @default.
• W2063341874 cites W2171662529 @default.
• W2063341874 cites W2335631045 @default.
• W2063341874 cites W2596624061 @default.
• W2063341874 cites W3198570063 @default.
• W2063341874 cites W1971653143 @default.
• W2063341874 doi "https://doi.org/10.2337/dc11-s241" @default.
• W2063341874 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3632195" @default.
• W2063341874 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21525471" @default.
• W2063341874 hasPublicationYear "2011" @default.
• W2063341874 type Work @default.
• W2063341874 sameAs 2063341874 @default.
• W2063341874 citedByCount "31" @default.
• W2063341874 countsByYear W20633418742012 @default.
• W2063341874 countsByYear W20633418742013 @default.
• W2063341874 countsByYear W20633418742014 @default.
• W2063341874 countsByYear W20633418742015 @default.
• W2063341874 countsByYear W20633418742016 @default.
• W2063341874 countsByYear W20633418742017 @default.
• W2063341874 countsByYear W20633418742018 @default.
• W2063341874 countsByYear W20633418742019 @default.
• W2063341874 countsByYear W20633418742020 @default.
• W2063341874 countsByYear W20633418742021 @default.
• W2063341874 countsByYear W20633418742022 @default.
• W2063341874 countsByYear W20633418742023 @default.
• W2063341874 crossrefType "journal-article" @default.
• W2063341874 hasAuthorship W2063341874A5032861135 @default.
• W2063341874 hasAuthorship W2063341874A5059051905 @default.
• W2063341874 hasBestOaLocation W20633418741 @default.
• W2063341874 hasConcept C126322002 @default.
• W2063341874 hasConcept C134018914 @default.
• W2063341874 hasConcept C2779922275 @default.
• W2063341874 hasConcept C2781184683 @default.
• W2063341874 hasConcept C555293320 @default.
• W2063341874 hasConcept C71924100 @default.
• W2063341874 hasConceptScore W2063341874C126322002 @default.
• W2063341874 hasConceptScore W2063341874C134018914 @default.
• W2063341874 hasConceptScore W2063341874C2779922275 @default.
• W2063341874 hasConceptScore W2063341874C2781184683 @default.

• next