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- W2063345981 abstract "Abstract Preparation of 1-methylpyrrole-2-acetonitrile, 1-methyl-5-(4-methylbenzoyl) pyrrole-2-acetonitrile and 2-(6-methoxy-2-naphthyl)propionitrile by treatment of 1-methylpyrrole-2-carboxaldehyde, 1-methyl-5-(4-methylbenzoyl)pyrrole-2-carboxaldehyde and, respectively, 6-methoxy-2-acetylnaphthalene with tosylmethylisocyanide (TosMIC) is described. This one-step synthetic procedure is very useful to obtain the nitrile precursors of tolmetin and naproxen, two clinically important non-steroidal antiinflammatory agents (NSAIAs)." @default.
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- W2063345981 date "1995-03-01" @default.
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- W2063345981 title "Simple Synthetic Approach to Arylacetic NsaiasviaTosMIC Procedure" @default.
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- W2063345981 doi "https://doi.org/10.1080/00397919508013414" @default.
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