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- W2063359178 abstract "A major aim of minimally invasive neurosurgery is to preserve function in the brain and cranial nerves. Based on previous results of radiosurgery for central lesions (19 craniopharyngiomas, 46 pituitary adenomas, 9 meningeal tumors), combined micro-and/or radiosurgery was applied for large lesions compressing the hypothalamus and/or brainstem. A basal interhemispheric approach via superomedial orbitotomy or a transcallosal-transforaminal approach was used for these large tumors. Tumors left behind in the hypothalamus or cavernous sinus were treated with radiosurgery using a gamma unit. Preoperative hypothalamo-pituitary functions were preserved in most of these patients. Radiosurgical results were evaluated in patients followed for more than 2 years after treatment. All 9 craniopharyngiomas decreased in size after radiosurgery, although a second treatment was required in 4 patients. All 20 pituitary adenomas were stable or decreased in size and 5 of 7 functioning adenomas showed normalized values of hormones in the serum. All 3 meningeal tumors were stable or decreased in size after treatment. No cavernous sinus symptoms developed after radiosurgery. We conclude that combined micro-and radio-neurosurgery is an effective and less invasive treatment for large central lesions compressing the hypothalamus and brainstem." @default.
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- W2063359178 date "1998-01-01" @default.
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- W2063359178 title "LARGE CENTRAL LESIONS COMPRESSING THE HYPOTHALAMUS AND BRAINSTEM :" @default.
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- W2063359178 doi "https://doi.org/10.2974/kmj.48.special1_71" @default.
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