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- W2063384328 abstract "This study was designed to demonstrate that properties of a granulation with a given composition, prepared by the spheronizing technique, could be altered by slight changes in process variables alone to satisfy the requirements of the formulator. A complete factorial experimental design was found satisfactory for demonstrating the range of properties to be expected and for showing statistically significant main effects and any linear interactions between selected variables. Results using two levels of five variables showed that initial water content and spheronizer speed had significant main effects on all primary granulation properties studied. While only one formulation was studied, the data suggest that the factorial design can have utility in predicting the properties of granulations prepared at conditions within the limits imposed by the equipment or formulation." @default.
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- W2063384328 date "1975-10-01" @default.
- W2063384328 modified "2023-09-26" @default.
- W2063384328 title "Use of Factorial Design to Evaluate Granulations Prepared by Spheronization" @default.
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- W2063384328 doi "https://doi.org/10.1002/jps.2600641023" @default.
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