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- W2063410606 abstract "T lymphocytes play critical roles in a series of important immune responses, including delayed-type hypersensitivity and contact sensitivity. Metal haptens such as nickel are among the most common sensitizers. In general, T cells recognize fragments of proteins complexed to MHC molecules. Haptens, however, are too small to be antigenic by themselves. Recent experiments have suggested that hapten-specific T cells recognize hapten-modified MHC-peptide complexes. Here I review the data supporting this hypothesis and speculate on the relevance of these findings for the understanding of chemical-induced hypersensitivities." @default.
- W2063410606 created "2016-06-24" @default.
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- W2063410606 date "1994-04-01" @default.
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- W2063410606 title "The Molecular Basis of Metal Recognition by T Cells" @default.
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- W2063410606 doi "https://doi.org/10.1111/1523-1747.ep12372149" @default.
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