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- W2063431942 abstract "The effects of different doses of scopolamine, and of the nootropic drugs oxiracetam and aniracetam, were investigated on the performance of male Wistar rats in a T-maze requiring a spatial discrimination in the stem (reference memory) and an alternate discrimination in the arms (working memory). Criterion (90% correct responses) was reached within 3 days of daily training for stem and 9 days for arm discrimination. Scopolamine (0.1, 0.2, 0.6, and 1.0 mg/kg, SC, 60 min before session) significantly impaired working memory, as shown by a decrease in the number of correct alternations, without affecting reference memory. Both nootropic drugs (25-50 and 100 mg/kg PO) 30 min before scopolamine) attenuated the working memory impairment induced by scopolamine." @default.
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- W2063431942 date "1992-12-01" @default.
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- W2063431942 title "Effect of scopolamine and nootropic drugs on rewarded alternation in a T-maze" @default.
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- W2063431942 doi "https://doi.org/10.1016/0091-3057(92)90497-4" @default.
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