FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2063437716> ?p ?o ?g. }

• W2063437716 endingPage "167" @default.
• W2063437716 startingPage "156" @default.
• W2063437716 abstract "<i>Background:</i> Monocytes, macrophages, and antigen-presenting cells (APCs) are key effectors of both innate and acquired immune responses. Such cells have been implicated in the pathogenesis of some inflammatory diseases. Differential gene expression in CD14-positive cells from patients with atopic dermatitis (AD) was studied using real-time quantitative RT-PCR to measure transcription levels of selected genes. <i>Methods:</i> PBMCs were prepared by Ficoll gradient separation from 30 AD patients (the anti-mite-specific IgE RAST score: 0.75 to >100 UA/ml) and 10 healthy adult individuals (the RAST score: <0.34–0.37 UA/ml) and CD14-positive cells were selected. A total of 64 genes was selected for study from groups of genes with different molecular function. <i>Results:</i> Genes involved in MHC class I antigen presentation, such as β₂-microglobulin, subunits of an immunoproteasome and ATP-binding cassette transporter TAP2 were expressed at higher levels in the AD patients than in the healthy controls. The genes for Toll-like receptors, CD36 and IFNγ receptor were also upregulated in the AD patients. These genes are involved in MHC class I antigen presentation, recognition of bacterial pathogens and apoptotic cells. <i>Conclusions:</i> The upregulation of genes suggests that circulating monocytes in AD patients may be primed to differentiate into effector cells by conditions associated with AD. The upregulation of genes may prove to be a useful marker for AD." @default.
• W2063437716 created "2016-06-24" @default.
• W2063437716 creator A5007542745 @default.
• W2063437716 creator A5015578380 @default.
• W2063437716 creator A5028205030 @default.
• W2063437716 creator A5039560593 @default.
• W2063437716 creator A5045926447 @default.
• W2063437716 creator A5060076818 @default.
• W2063437716 creator A5068221721 @default.
• W2063437716 creator A5074728289 @default.
• W2063437716 creator A5087874720 @default.
• W2063437716 date "2003-01-01" @default.
• W2063437716 modified "2023-10-16" @default.
• W2063437716 title "Analysis of Highly Expressed Genes in Monocytes from Atopic Dermatitis Patients" @default.
• W2063437716 cites W1680217275 @default.
• W2063437716 cites W1930598094 @default.
• W2063437716 cites W1970846519 @default.
• W2063437716 cites W1996224887 @default.
• W2063437716 cites W1997409891 @default.
• W2063437716 cites W2016862474 @default.
• W2063437716 cites W2028699526 @default.
• W2063437716 cites W2053183695 @default.
• W2063437716 cites W2053849689 @default.
• W2063437716 cites W2073017063 @default.
• W2063437716 cites W2094563797 @default.
• W2063437716 cites W2122048526 @default.
• W2063437716 cites W2124458096 @default.
• W2063437716 cites W2155580702 @default.
• W2063437716 cites W2159316425 @default.
• W2063437716 cites W2159795335 @default.
• W2063437716 cites W4239498949 @default.
• W2063437716 doi "https://doi.org/10.1159/000073717" @default.
• W2063437716 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/14600428" @default.
• W2063437716 hasPublicationYear "2003" @default.
• W2063437716 type Work @default.
• W2063437716 sameAs 2063437716 @default.
• W2063437716 citedByCount "24" @default.
• W2063437716 countsByYear W20634377162012 @default.
• W2063437716 countsByYear W20634377162014 @default.
• W2063437716 countsByYear W20634377162015 @default.
• W2063437716 countsByYear W20634377162019 @default.
• W2063437716 countsByYear W20634377162022 @default.
• W2063437716 countsByYear W20634377162023 @default.
• W2063437716 crossrefType "journal-article" @default.
• W2063437716 hasAuthorship W2063437716A5007542745 @default.
• W2063437716 hasAuthorship W2063437716A5015578380 @default.
• W2063437716 hasAuthorship W2063437716A5028205030 @default.
• W2063437716 hasAuthorship W2063437716A5039560593 @default.
• W2063437716 hasAuthorship W2063437716A5045926447 @default.
• W2063437716 hasAuthorship W2063437716A5060076818 @default.
• W2063437716 hasAuthorship W2063437716A5068221721 @default.
• W2063437716 hasAuthorship W2063437716A5074728289 @default.
• W2063437716 hasAuthorship W2063437716A5087874720 @default.
• W2063437716 hasConcept C104317684 @default.
• W2063437716 hasConcept C127561419 @default.
• W2063437716 hasConcept C147483822 @default.
• W2063437716 hasConcept C153911025 @default.
• W2063437716 hasConcept C170627219 @default.
• W2063437716 hasConcept C203014093 @default.
• W2063437716 hasConcept C207936829 @default.
• W2063437716 hasConcept C2776090121 @default.
• W2063437716 hasConcept C2778513237 @default.
• W2063437716 hasConcept C54355233 @default.
• W2063437716 hasConcept C83464605 @default.
• W2063437716 hasConcept C86803240 @default.
• W2063437716 hasConcept C8891405 @default.
• W2063437716 hasConceptScore W2063437716C104317684 @default.
• W2063437716 hasConceptScore W2063437716C127561419 @default.
• W2063437716 hasConceptScore W2063437716C147483822 @default.
• W2063437716 hasConceptScore W2063437716C153911025 @default.
• W2063437716 hasConceptScore W2063437716C170627219 @default.
• W2063437716 hasConceptScore W2063437716C203014093 @default.
• W2063437716 hasConceptScore W2063437716C207936829 @default.
• W2063437716 hasConceptScore W2063437716C2776090121 @default.
• W2063437716 hasConceptScore W2063437716C2778513237 @default.
• W2063437716 hasConceptScore W2063437716C54355233 @default.
• W2063437716 hasConceptScore W2063437716C83464605 @default.
• W2063437716 hasConceptScore W2063437716C86803240 @default.
• W2063437716 hasConceptScore W2063437716C8891405 @default.
• W2063437716 hasIssue "2" @default.
• W2063437716 hasLocation W20634377161 @default.
• W2063437716 hasLocation W20634377162 @default.
• W2063437716 hasOpenAccess W2063437716 @default.
• W2063437716 hasPrimaryLocation W20634377161 @default.
• W2063437716 hasRelatedWork W1840653008 @default.
• W2063437716 hasRelatedWork W1939527068 @default.
• W2063437716 hasRelatedWork W1972434619 @default.
• W2063437716 hasRelatedWork W2023967363 @default.
• W2063437716 hasRelatedWork W2041638315 @default.
• W2063437716 hasRelatedWork W2061366633 @default.
• W2063437716 hasRelatedWork W2107554173 @default.
• W2063437716 hasRelatedWork W2126139339 @default.
• W2063437716 hasRelatedWork W2977793531 @default.
• W2063437716 hasRelatedWork W4244317160 @default.
• W2063437716 hasVolume "132" @default.
• W2063437716 isParatext "false" @default.
• W2063437716 isRetracted "false" @default.
• W2063437716 magId "2063437716" @default.

• next