Matches in SemOpenAlex for { <https://semopenalex.org/work/W2063460766> ?p ?o ?g. }
- W2063460766 endingPage "419" @default.
- W2063460766 startingPage "412" @default.
- W2063460766 abstract "This study was designed to investigate the effects of local delivery of bone marrow mesenchymal stem cells (BMMSCs) with or without osterix (OSX) gene transfected on bone regeneration in the distracted zone using a rabbit model of mandibular lengthening. Fifty-four New Zealand white rabbits underwent osteodistraction of the left mandible and were then randomly divided into group A, group B, and group C (n = 18 for each group). At the end of distraction BMMSCs transfected with OSX, autologous BMMSCs and physiological saline were injected into the distraction gaps in groups A, B, and C, respectively. Nine animals from each group were humanely killed at 2 and 6 weeks after completion of distraction. The distracted mandibles were harvested and processed for radiographic, histological, and immunohistochemical examination. Excellent bone formation in the distracted callus was observed in group A and group B; the former showed better bone formation and highest bone mineral density (BMD), thickness of new trabeculae (TNT, mm) and volumes of the newly formed bone area (NBV) in the distraction zones. Group C animals showed poor bone formation in the distracted callus when compared with groups A and B. Positive immunostaining of bone sialoprotein (BSP) was observed in the distracted callus in all groups; however, BSP expression was much stronger in group A than in groups B and C. The results of this study suggest transplantation of BMMSCs can promote bone formation in DO; OSX-mediated ex vivo gene therapy was more effective during bone deposition and callus formation in distraction osteogenesis." @default.
- W2063460766 created "2016-06-24" @default.
- W2063460766 creator A5015394118 @default.
- W2063460766 creator A5025499451 @default.
- W2063460766 creator A5027697637 @default.
- W2063460766 creator A5039360168 @default.
- W2063460766 creator A5047669982 @default.
- W2063460766 creator A5051069528 @default.
- W2063460766 creator A5053892310 @default.
- W2063460766 creator A5070321959 @default.
- W2063460766 creator A5070369693 @default.
- W2063460766 creator A5079629617 @default.
- W2063460766 date "2011-04-01" @default.
- W2063460766 modified "2023-09-27" @default.
- W2063460766 title "Transcription factor osterix modified bone marrow mesenchymal stem cells enhance callus formation during distraction osteogenesis" @default.
- W2063460766 cites W1523690135 @default.
- W2063460766 cites W1964366331 @default.
- W2063460766 cites W1968454015 @default.
- W2063460766 cites W1969108838 @default.
- W2063460766 cites W1972389555 @default.
- W2063460766 cites W1977900423 @default.
- W2063460766 cites W1978091672 @default.
- W2063460766 cites W1981120621 @default.
- W2063460766 cites W1993640536 @default.
- W2063460766 cites W1994596418 @default.
- W2063460766 cites W1999070656 @default.
- W2063460766 cites W2004895813 @default.
- W2063460766 cites W2009331385 @default.
- W2063460766 cites W2009515190 @default.
- W2063460766 cites W2014673628 @default.
- W2063460766 cites W2015404892 @default.
- W2063460766 cites W2016985748 @default.
- W2063460766 cites W2019480285 @default.
- W2063460766 cites W2031490425 @default.
- W2063460766 cites W2038543234 @default.
- W2063460766 cites W2055124161 @default.
- W2063460766 cites W2059437783 @default.
- W2063460766 cites W2062276394 @default.
- W2063460766 cites W2062685681 @default.
- W2063460766 cites W2066260122 @default.
- W2063460766 cites W2066516540 @default.
- W2063460766 cites W2068102253 @default.
- W2063460766 cites W2077548451 @default.
- W2063460766 cites W2084135855 @default.
- W2063460766 cites W2087987629 @default.
- W2063460766 cites W2095018567 @default.
- W2063460766 cites W2095774314 @default.
- W2063460766 cites W2109404976 @default.
- W2063460766 cites W2120410243 @default.
- W2063460766 cites W2122367477 @default.
- W2063460766 cites W2131862834 @default.
- W2063460766 cites W2145456538 @default.
- W2063460766 cites W2152508822 @default.
- W2063460766 cites W2163995267 @default.
- W2063460766 cites W2293262216 @default.
- W2063460766 cites W2327917107 @default.
- W2063460766 cites W4251017579 @default.
- W2063460766 doi "https://doi.org/10.1016/j.tripleo.2010.05.012" @default.
- W2063460766 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20813560" @default.
- W2063460766 hasPublicationYear "2011" @default.
- W2063460766 type Work @default.
- W2063460766 sameAs 2063460766 @default.
- W2063460766 citedByCount "32" @default.
- W2063460766 countsByYear W20634607662012 @default.
- W2063460766 countsByYear W20634607662013 @default.
- W2063460766 countsByYear W20634607662014 @default.
- W2063460766 countsByYear W20634607662015 @default.
- W2063460766 countsByYear W20634607662016 @default.
- W2063460766 countsByYear W20634607662017 @default.
- W2063460766 countsByYear W20634607662018 @default.
- W2063460766 countsByYear W20634607662019 @default.
- W2063460766 countsByYear W20634607662020 @default.
- W2063460766 countsByYear W20634607662021 @default.
- W2063460766 countsByYear W20634607662022 @default.
- W2063460766 countsByYear W20634607662023 @default.
- W2063460766 crossrefType "journal-article" @default.
- W2063460766 hasAuthorship W2063460766A5015394118 @default.
- W2063460766 hasAuthorship W2063460766A5025499451 @default.
- W2063460766 hasAuthorship W2063460766A5027697637 @default.
- W2063460766 hasAuthorship W2063460766A5039360168 @default.
- W2063460766 hasAuthorship W2063460766A5047669982 @default.
- W2063460766 hasAuthorship W2063460766A5051069528 @default.
- W2063460766 hasAuthorship W2063460766A5053892310 @default.
- W2063460766 hasAuthorship W2063460766A5070321959 @default.
- W2063460766 hasAuthorship W2063460766A5070369693 @default.
- W2063460766 hasAuthorship W2063460766A5079629617 @default.
- W2063460766 hasConcept C105702510 @default.
- W2063460766 hasConcept C131075544 @default.
- W2063460766 hasConcept C142724271 @default.
- W2063460766 hasConcept C157369684 @default.
- W2063460766 hasConcept C160160445 @default.
- W2063460766 hasConcept C16685009 @default.
- W2063460766 hasConcept C169760540 @default.
- W2063460766 hasConcept C181199279 @default.
- W2063460766 hasConcept C185592680 @default.
- W2063460766 hasConcept C198826908 @default.
- W2063460766 hasConcept C204232928 @default.
- W2063460766 hasConcept C2776378700 @default.