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• W2063471912 abstract "THE LATE 1960s and early 1970s were a time of rapid progress in the treatment of childhood cancer, particularly in North America and Western Europe. The impact of multicentre clinical trials run by the Children’s Cancer Study Group (CCSG, now CCG) and Pediatric Oncology Group (POG) in the U.S. disseminated widely the benefits of the treatment advances pioneered in some of the individual major cancer centres. In Europe, the International Society of Paediatric Oncology (SIOP) drew together researchers from the main centres in the same way and provided an annual forum to update results from their own trials and the major U.S. trials, in particular those of the Intergroup (Wilms’, rhabdomyosarcoma, Ewing’s) studies. Young investigators interested in paediatric malignancy were able to use the contacts made within SIOP to arrange training opportunities across international boundaries and on their return to their home institution invigorated them with new ways of thinking about old problems. In the U.K. a few multicentre clinical trials took place under the auspices of the Medical Research Council (for leukaemias, Wilms’ tumour and osteosarcoma) and some major centres contributed actively to SIOP trials on rhabdomyosarcoma and medulloblastoma. However, it became increasingly apparent that a new national organisation was required if children nationwide were going to benefit promptly from the advances being made. On 14 January 1977, a meeting was held in the Birmingham Children’s Hospital at which 14 members from 7 paediatric oncology units agreed to form the UKCCSG. This core group, which was augmented by invited representatives of 6 other units, was multidisciplinary and included paediatric oncologists, haematologists, surgeons, radiotherapists and pathologists. Half of its original members are still active participants of the group 20 years later. The membership of the UKCCSG now totals 220 full and associate members, 20 affiliates (consultants in shared care centres), 24 corresponding (overseas), 6 honorary and 17 junior members (trainees). At that inaugural meeting, the aims of the group were agreed to include the establishment of cooperative groups" @default.
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• W2063471912 date "1997-08-01" @default.
• W2063471912 modified "2023-09-24" @default.
• W2063471912 title "The United Kingdom children's cancer study group—the first 20 years of growth and development" @default.
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• W2063471912 doi "https://doi.org/10.1016/s0959-8049(97)00250-5" @default.
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