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- W2063482010 abstract "Rat tracheal explants maintained as organ cultures exhibited a normal mucociliary epithelium for at least 46 days in the presence of retinyl acetate. In the absence of vitamin A the explant epithelium became quiescent or underwent a metaplastic change to a keratinizing squamous epithelium. This process was accelerated if explants were derived from vitamin A-deficient animals. Autoradiographic examination showed that [3H]glucosamine label accumulated in various cell types in the explant, but especially in the epithelium. It was found that the explants secreted mucous glycoproteins into the medium and that the production and biochemical characteristics of a specific mucin fraction were dependent upon the vitamin A status of the explant." @default.
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- W2063482010 date "1979-09-01" @default.
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- W2063482010 title "The Effect of Vitamin A on Cellular Differentiation and Mucous Glycoprotein Synthesis in Long-Term Rat Tracheal Organ Cultures" @default.
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- W2063482010 doi "https://doi.org/10.1111/j.1432-0436.1979.tb01026.x" @default.
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