Matches in SemOpenAlex for { <https://semopenalex.org/work/W2063491172> ?p ?o ?g. }
Showing items 1 to 92 of
92
with 100 items per page.
- W2063491172 endingPage "S19" @default.
- W2063491172 startingPage "S17" @default.
- W2063491172 abstract "Abstract Objective To evaluate the antidepressant activity of methanolic extract of rhizomes of Acorus calamus ( A. calamus ). Methods Tail suspension test (TST) and forced swimming test (FST) in mice were used to evaluate the antidepressant activity of methanolic extract of rhizomes of A. calamus . Methanolic extracts (50 and 100 mg/kg i.p.) were administered daily for 7 days. Imipramine 5 mg/kg was used as standard antidepressant agent throughout the study. Results Test extracts of A. calamus decreased immobility periods significantly in a dose dependent manner in both TST and FST. The observed results were also comparable with known standard drug i.e. imipramine. The flavonoid apigenin, which selectively binds with high affinity to the central benzodiazepines receptor, possesses important anxiolytic and antidepressant activities. The review of literature reveals that the A. calamus contains saponin, glycosides, tannin and flavonoid. Conclusions Methanolic extract of A. calamus rhizomes shows antidepressant activity probably through interaction with adrenergic, dopaminergic serotonergic and γ-aminobutyric acid (GABA) nergic system. Both the models have been proved to be equally valuable for demonstration of substances with a potential antidepressant activity." @default.
- W2063491172 created "2016-06-24" @default.
- W2063491172 creator A5004422296 @default.
- W2063491172 creator A5027495073 @default.
- W2063491172 creator A5027691181 @default.
- W2063491172 creator A5077384449 @default.
- W2063491172 date "2011-09-01" @default.
- W2063491172 modified "2023-10-09" @default.
- W2063491172 title "Antidepressant–like effects of Acorus calamus in forced swimming and tail suspension test in mice" @default.
- W2063491172 cites W1497985138 @default.
- W2063491172 cites W1971354069 @default.
- W2063491172 cites W1986095478 @default.
- W2063491172 cites W2003338094 @default.
- W2063491172 cites W2041016831 @default.
- W2063491172 cites W2044709062 @default.
- W2063491172 cites W2055643061 @default.
- W2063491172 cites W2063395206 @default.
- W2063491172 cites W2068144275 @default.
- W2063491172 cites W2086672378 @default.
- W2063491172 doi "https://doi.org/10.1016/s2221-1691(11)60114-7" @default.
- W2063491172 hasPublicationYear "2011" @default.
- W2063491172 type Work @default.
- W2063491172 sameAs 2063491172 @default.
- W2063491172 citedByCount "13" @default.
- W2063491172 countsByYear W20634911722013 @default.
- W2063491172 countsByYear W20634911722014 @default.
- W2063491172 countsByYear W20634911722015 @default.
- W2063491172 countsByYear W20634911722016 @default.
- W2063491172 countsByYear W20634911722017 @default.
- W2063491172 countsByYear W20634911722018 @default.
- W2063491172 countsByYear W20634911722020 @default.
- W2063491172 countsByYear W20634911722021 @default.
- W2063491172 countsByYear W20634911722022 @default.
- W2063491172 countsByYear W20634911722023 @default.
- W2063491172 crossrefType "journal-article" @default.
- W2063491172 hasAuthorship W2063491172A5004422296 @default.
- W2063491172 hasAuthorship W2063491172A5027495073 @default.
- W2063491172 hasAuthorship W2063491172A5027691181 @default.
- W2063491172 hasAuthorship W2063491172A5077384449 @default.
- W2063491172 hasConcept C105341887 @default.
- W2063491172 hasConcept C134550120 @default.
- W2063491172 hasConcept C136569192 @default.
- W2063491172 hasConcept C169760540 @default.
- W2063491172 hasConcept C202444582 @default.
- W2063491172 hasConcept C2776100074 @default.
- W2063491172 hasConcept C2779177272 @default.
- W2063491172 hasConcept C2781001258 @default.
- W2063491172 hasConcept C2781161787 @default.
- W2063491172 hasConcept C33070731 @default.
- W2063491172 hasConcept C33923547 @default.
- W2063491172 hasConcept C556039675 @default.
- W2063491172 hasConcept C5961521 @default.
- W2063491172 hasConcept C71924100 @default.
- W2063491172 hasConcept C86803240 @default.
- W2063491172 hasConcept C98274493 @default.
- W2063491172 hasConceptScore W2063491172C105341887 @default.
- W2063491172 hasConceptScore W2063491172C134550120 @default.
- W2063491172 hasConceptScore W2063491172C136569192 @default.
- W2063491172 hasConceptScore W2063491172C169760540 @default.
- W2063491172 hasConceptScore W2063491172C202444582 @default.
- W2063491172 hasConceptScore W2063491172C2776100074 @default.
- W2063491172 hasConceptScore W2063491172C2779177272 @default.
- W2063491172 hasConceptScore W2063491172C2781001258 @default.
- W2063491172 hasConceptScore W2063491172C2781161787 @default.
- W2063491172 hasConceptScore W2063491172C33070731 @default.
- W2063491172 hasConceptScore W2063491172C33923547 @default.
- W2063491172 hasConceptScore W2063491172C556039675 @default.
- W2063491172 hasConceptScore W2063491172C5961521 @default.
- W2063491172 hasConceptScore W2063491172C71924100 @default.
- W2063491172 hasConceptScore W2063491172C86803240 @default.
- W2063491172 hasConceptScore W2063491172C98274493 @default.
- W2063491172 hasIssue "1" @default.
- W2063491172 hasLocation W20634911721 @default.
- W2063491172 hasOpenAccess W2063491172 @default.
- W2063491172 hasPrimaryLocation W20634911721 @default.
- W2063491172 hasRelatedWork W1659841086 @default.
- W2063491172 hasRelatedWork W1879189602 @default.
- W2063491172 hasRelatedWork W2031210349 @default.
- W2063491172 hasRelatedWork W2352403311 @default.
- W2063491172 hasRelatedWork W2377903598 @default.
- W2063491172 hasRelatedWork W2997436346 @default.
- W2063491172 hasRelatedWork W3022052974 @default.
- W2063491172 hasRelatedWork W3118587499 @default.
- W2063491172 hasRelatedWork W4238957905 @default.
- W2063491172 hasRelatedWork W2112322920 @default.
- W2063491172 hasVolume "1" @default.
- W2063491172 isParatext "false" @default.
- W2063491172 isRetracted "false" @default.
- W2063491172 magId "2063491172" @default.
- W2063491172 workType "article" @default.