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- W2063505819 abstract "S-ethyl dipropylthiocarbamate (EPTC) inhibited gibberellic acid (GA) precursor biosynthesis in a cell-free enzyme preparation from unruptured, etiolated sorghum (Sorghum bicolor L. cv. G522 DR) coleoptiles. EPTC, 1 μM, inhibited incorporation of [14C]mevalonic acid into kaurene 60%, while 10 μM EPTC inhibited 14C incorporation into kaurene 90%. The precursor of kaurene cyclization (GGPP) increased in 14C content at both EPTC concentrations. R-25788 reversed the EPTC inhibition of kaurene synthesis. Kaurene oxidation was modified by both EPTC and R-25788. Hypothesized modes of action for EPTC and R-25788 are (a) inhibition of GA synthesis, (b) increased peroxidase activity resulting in increased lignification, (c) increased detoxification by sulfoxidation and carbamoylation, and (d) inhibition of fatty acid synthesis and/or desaturation. These hypotheses are discussed with three of them being incorporated into one working unit which correlates with EPTC and R-25788 symptom phenology. The fourth hypothesis could also fit into this general pattern." @default.
- W2063505819 created "2016-06-24" @default.
- W2063505819 creator A5075526855 @default.
- W2063505819 date "1983-06-01" @default.
- W2063505819 modified "2023-10-14" @default.
- W2063505819 title "Gibberellin precursor biosynthesis inhibition by EPTC and reversal by R-25788" @default.
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- W2063505819 doi "https://doi.org/10.1016/0048-3575(83)90060-3" @default.
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