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- W2063519390 abstract "An automatic continuous-addition-of-reagent method for the routine determination of oxazepam based on the formation of a coupling product between diazotized 2-amine-5-chlorobenzophenone (the hydrolysis product of oxazepam) and 1-naphthol in a basic medium is proposed. The reaction is developed by continuously adding basic 1-naphthol to a reaction vessel containing the other ingredients and is monitored spectrophotometrically at 530 nm. The results obtained show the proposed kinetic method to surpass the performance of its conventional equilibrium counterpart as it permits distinguishing the intact drug from its hydrolytic degradation product and is suitable for the determination of oxazepam in dosage forms and urine samples." @default.
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- W2063519390 date "1992-09-01" @default.
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- W2063519390 title "Automatic kinetic determination of oxazepam by the continuous addition of reagent technique" @default.
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- W2063519390 doi "https://doi.org/10.1016/0039-9140(92)80216-z" @default.
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