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- W2063526400 abstract "Fourteen patients with chronic genital warts were entered in a pair-matched crossover trial of recombinant interferon-α-2a. They received daily doses of either 1.5 × 106 U or 18 × 106 U interferon for one week by the subcutaneous route (abdominal skin). After an observation period of 4 weeks in case of no change or partial response, patients of the low-dose group were given 18 × 106 U and those of the high-dose group 3 × 106 U daily for another 7 days. Eight of 14 patients had a complete remission by the end of the therapy-free interval of 4 weeks, 5 patients of the low-dose group and 3 patients of the high-dose group. Acute side-effects consisted of a transient influenza-like syndrome. Remissions have been maintained for 6 to over 10 months. The data implicate that recombinant interferon-α-2a is highly effective in patients with human papillomavirus-related genital warts and that the low-dose regimen is at least equivalent to the high-dose treatment." @default.
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- W2063526400 date "1986-01-01" @default.
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- W2063526400 title "Systemic Treatment of Condylomata Acuminata with Recombinant Interferon-Alpha-2A: Low-Dose Superior to the High-Dose Regimen" @default.
- W2063526400 doi "https://doi.org/10.1159/000238464" @default.
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