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- W2063546002 abstract "Our aim was to study the effect, during the period 1979–1996, of the potential risk factors (i) year, age at second visit and first screening interval on the frequency of detection of low- and high-grade smears at the second visit after a normal smear at the first visit; (ii) year, age at second visit and low-grade smears at first visit on the detection of high-grade smears at second visit; (iii) detection of low- and high-grade smears by calendar year at second visit after a normal first visit (period 1981–1996); (iv) proportion of high-grade smears at second visit attributable to low-grade smears at first visit (exposed group); and (v) effect of increasing the screening interval from 2 to 5 years. The results were as follows: (i) low-grade smears increased significantly with years, high-grade smears increased significantly with screening interval and both grades decreased significantly with age; (ii) high-grade smears increased significantly with low-grade smears at first visit and with year but decreased significantly with age; (iii) a significant increase in low-grade smears at second visit with years; (iv) 97% of high-grade smears at second visit were attributable to low-grade smears at first visit; and (v) the risk of high-grade smears was 60% higher when the screening interval was 5 years rather than 2 years after a normal visit at age 20. The strongest risk factors for high-grade cell changes were low-grade smears at first visit [odds ratio 10.2 (ii) and 29.0 (iv)] and first screening interval [odds ratio 1.6 (v)]. © 2001 Wiley-Liss, Inc." @default.
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- W2063546002 date "2001-01-01" @default.
- W2063546002 modified "2023-10-12" @default.
- W2063546002 title "Risk variables affecting high-grade pap smears at second visit: Effects of screening interval, year, age and low-grade smears" @default.
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- W2063546002 doi "https://doi.org/10.1002/ijc.1546" @default.
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