FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2063558406> ?p ?o ?g. }

• W2063558406 endingPage "736" @default.
• W2063558406 startingPage "729" @default.
• W2063558406 abstract "Well-differentiated spindle cell liposarcoma represents a rare atypical/low-grade malignant lipogenic neoplasm that has been regarded as a variant of atypical lipomatous tumor. However, well-differentiated spindle cell liposarcoma tends to occur in subcutaneous tissue of the extremities, the trunk, and the head and neck region, contains slightly atypical spindled tumor cells often staining positively for CD34, and lacks an amplification of MDM2 and/or CDK4 in most of the cases analyzed. We studied a series of well-differentiated spindle cell liposarcomas arising in two female and four male patients (age of the patients ranged from 59 to 85 years). The neoplasms arose on the shoulder, the chest wall, the thigh, the lower leg, the back of the hand, and in paratesticular location. The size of the neoplasms ranged from 1.5 to 10 cm (mean: 6.0 cm). All neoplasms were completely excised. The neoplasms were confined to the subcutis in three cases, and in three cases, an infiltration of skeletal muscle was seen. Histologically, the variably cellular neoplasms were composed of atypical lipogenic cells showing variations in size and shape, and spindled tumor cells with slightly enlarged, often hyperchromatic nuclei. Multivacuolated lipoblasts were present in three neoplasms. Focal myxoid stromal changes were seen in three cases. Immunohistochemically, CD34 was at least focally positive in all cases, whereas scattered tumor cells only showed a nuclear expression of MDM2 in two neoplasms. FISH analysis revealed a deletion of the Rb-1 gene in all six cases, whereas no MDM2/CDK4 amplification was identified in all cases tested. Follow-up information was available in four cases (range from 4 to 24 months), and revealed a local recurrence in one case. Although well-differentiated spindle cell liposarcoma and atypical lipomatous tumor behave clinically similar, it can be speculated on the basis of clinicopathologic and molecular findings that well-differentiated spindle cell liposarcoma may constitute an independent entity rather than a morphologic variant of atypical lipomatous tumor, and may represent the atypical/low-grade counterpart of spindle cell lipoma." @default.
• W2063558406 created "2016-06-24" @default.
• W2063558406 creator A5003654944 @default.
• W2063558406 creator A5009023383 @default.
• W2063558406 creator A5036798195 @default.
• W2063558406 date "2010-05-01" @default.
• W2063558406 modified "2023-10-14" @default.
• W2063558406 title "Well-differentiated spindle cell liposarcoma (‘atypical spindle cell lipomatous tumor‘) does not belong to the spectrum of atypical lipomatous tumor but has a close relationship to spindle cell lipoma: clinicopathologic, immunohistochemical, and molecular analysis of six cases" @default.
• W2063558406 cites W1974930895 @default.
• W2063558406 cites W1993350109 @default.
• W2063558406 cites W2011273926 @default.
• W2063558406 cites W2023789937 @default.
• W2063558406 cites W2023811225 @default.
• W2063558406 cites W2029140532 @default.
• W2063558406 cites W2053776753 @default.
• W2063558406 cites W2060649280 @default.
• W2063558406 cites W2073448876 @default.
• W2063558406 cites W2073533521 @default.
• W2063558406 cites W2076746920 @default.
• W2063558406 cites W2087499760 @default.
• W2063558406 cites W2090890813 @default.
• W2063558406 cites W2095715463 @default.
• W2063558406 cites W2316911807 @default.
• W2063558406 cites W4255286029 @default.
• W2063558406 doi "https://doi.org/10.1038/modpathol.2010.66" @default.
• W2063558406 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20228779" @default.
• W2063558406 hasPublicationYear "2010" @default.
• W2063558406 type Work @default.
• W2063558406 sameAs 2063558406 @default.
• W2063558406 citedByCount "101" @default.
• W2063558406 countsByYear W20635584062012 @default.
• W2063558406 countsByYear W20635584062013 @default.
• W2063558406 countsByYear W20635584062014 @default.
• W2063558406 countsByYear W20635584062015 @default.
• W2063558406 countsByYear W20635584062016 @default.
• W2063558406 countsByYear W20635584062017 @default.
• W2063558406 countsByYear W20635584062018 @default.
• W2063558406 countsByYear W20635584062019 @default.
• W2063558406 countsByYear W20635584062020 @default.
• W2063558406 countsByYear W20635584062021 @default.
• W2063558406 countsByYear W20635584062022 @default.
• W2063558406 countsByYear W20635584062023 @default.
• W2063558406 crossrefType "journal-article" @default.
• W2063558406 hasAuthorship W2063558406A5003654944 @default.
• W2063558406 hasAuthorship W2063558406A5009023383 @default.
• W2063558406 hasAuthorship W2063558406A5036798195 @default.
• W2063558406 hasBestOaLocation W20635584061 @default.
• W2063558406 hasConcept C10205521 @default.
• W2063558406 hasConcept C105702510 @default.
• W2063558406 hasConcept C142724271 @default.
• W2063558406 hasConcept C204232928 @default.
• W2063558406 hasConcept C2776730994 @default.
• W2063558406 hasConcept C2778256501 @default.
• W2063558406 hasConcept C2779568860 @default.
• W2063558406 hasConcept C28328180 @default.
• W2063558406 hasConcept C54355233 @default.
• W2063558406 hasConcept C71924100 @default.
• W2063558406 hasConcept C86803240 @default.
• W2063558406 hasConceptScore W2063558406C10205521 @default.
• W2063558406 hasConceptScore W2063558406C105702510 @default.
• W2063558406 hasConceptScore W2063558406C142724271 @default.
• W2063558406 hasConceptScore W2063558406C204232928 @default.
• W2063558406 hasConceptScore W2063558406C2776730994 @default.
• W2063558406 hasConceptScore W2063558406C2778256501 @default.
• W2063558406 hasConceptScore W2063558406C2779568860 @default.
• W2063558406 hasConceptScore W2063558406C28328180 @default.
• W2063558406 hasConceptScore W2063558406C54355233 @default.
• W2063558406 hasConceptScore W2063558406C71924100 @default.
• W2063558406 hasConceptScore W2063558406C86803240 @default.
• W2063558406 hasIssue "5" @default.
• W2063558406 hasLocation W20635584061 @default.
• W2063558406 hasLocation W20635584062 @default.
• W2063558406 hasOpenAccess W2063558406 @default.
• W2063558406 hasPrimaryLocation W20635584061 @default.
• W2063558406 hasRelatedWork W157516211 @default.
• W2063558406 hasRelatedWork W2041286282 @default.
• W2063558406 hasRelatedWork W2057590271 @default.
• W2063558406 hasRelatedWork W2062643603 @default.
• W2063558406 hasRelatedWork W2070264952 @default.
• W2063558406 hasRelatedWork W2087178390 @default.
• W2063558406 hasRelatedWork W2163172836 @default.
• W2063558406 hasRelatedWork W2315056350 @default.
• W2063558406 hasRelatedWork W4299534754 @default.
• W2063558406 hasRelatedWork W2184220852 @default.
• W2063558406 hasVolume "23" @default.
• W2063558406 isParatext "false" @default.
• W2063558406 isRetracted "false" @default.
• W2063558406 magId "2063558406" @default.
• W2063558406 workType "article" @default.