FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2063587016> ?p ?o ?g. }

• W2063587016 endingPage "257" @default.
• W2063587016 startingPage "253" @default.
• W2063587016 abstract "Hormonal inductions of lipogenic enzyme activities (fatty acid synthetase, malic enzyme (ME), glucose-6-phosphate dehydrogenase (G6PD) and ATP-citrate lyase) were studied in primary cultured rat hepatocytes. Insulin, triiodothyronine and dexamethasone markedly stimulated the inductions of the enzymes (particularly G6PD and ME) in the presence of pyruvate. Lactate also induced their activities. The activities of these enzymes in the presence of appropriate hormone combinations and a substrate amount of pyruvate were as high as, or higher than those in the liver of rats on high-carbohydrate, low-fat diet. The aldolase and glucokinase activities induced by these hormones were not enhanced by the addition of pyruvate. The induction by pyruvate was inhibited by actinomycin D or cycloheximide. The ATP content of rat hepatocytes was maintained without increase during culture with pyruvate for 6 days. These results indicate that the additions of pyruvate, or its metabolites to cultures of isolated hepatocytes have specific effects on the inductions of certain hepatic enzymes, possibly acting at the level of transcription. Their effects are similar to those of feeding a high-carbohydrate, low-fat diet to intact animals." @default.
• W2063587016 created "2016-06-24" @default.
• W2063587016 creator A5014708552 @default.
• W2063587016 creator A5060146442 @default.
• W2063587016 creator A5068723476 @default.
• W2063587016 creator A5077387796 @default.
• W2063587016 date "1993-11-01" @default.
• W2063587016 modified "2023-10-15" @default.
• W2063587016 title "Pyruvate stimulates hormonal induction of lipogenic enzymes in primary cultured rat hepatocytes" @default.
• W2063587016 cites W1541902039 @default.
• W2063587016 cites W1560037002 @default.
• W2063587016 cites W1595100801 @default.
• W2063587016 cites W1597415571 @default.
• W2063587016 cites W170239507 @default.
• W2063587016 cites W1775749144 @default.
• W2063587016 cites W1847173671 @default.
• W2063587016 cites W1887943548 @default.
• W2063587016 cites W1895522077 @default.
• W2063587016 cites W1946196397 @default.
• W2063587016 cites W2000954124 @default.
• W2063587016 cites W2004430749 @default.
• W2063587016 cites W2016458297 @default.
• W2063587016 cites W2045038478 @default.
• W2063587016 cites W2078489711 @default.
• W2063587016 cites W2081564664 @default.
• W2063587016 cites W2081989366 @default.
• W2063587016 cites W2108358343 @default.
• W2063587016 cites W2130755410 @default.
• W2063587016 cites W2206310676 @default.
• W2063587016 cites W2213385493 @default.
• W2063587016 cites W2322438766 @default.
• W2063587016 cites W3889518 @default.
• W2063587016 doi "https://doi.org/10.1016/0005-2760(93)90007-v" @default.
• W2063587016 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8218343" @default.
• W2063587016 hasPublicationYear "1993" @default.
• W2063587016 type Work @default.
• W2063587016 sameAs 2063587016 @default.
• W2063587016 citedByCount "10" @default.
• W2063587016 countsByYear W20635870162016 @default.
• W2063587016 crossrefType "journal-article" @default.
• W2063587016 hasAuthorship W2063587016A5014708552 @default.
• W2063587016 hasAuthorship W2063587016A5060146442 @default.
• W2063587016 hasAuthorship W2063587016A5068723476 @default.
• W2063587016 hasAuthorship W2063587016A5077387796 @default.
• W2063587016 hasConcept C101972281 @default.
• W2063587016 hasConcept C10730799 @default.
• W2063587016 hasConcept C126322002 @default.
• W2063587016 hasConcept C134018914 @default.
• W2063587016 hasConcept C140137476 @default.
• W2063587016 hasConcept C141359234 @default.
• W2063587016 hasConcept C181199279 @default.
• W2063587016 hasConcept C190098323 @default.
• W2063587016 hasConcept C20251656 @default.
• W2063587016 hasConcept C20904676 @default.
• W2063587016 hasConcept C2776317432 @default.
• W2063587016 hasConcept C2777318727 @default.
• W2063587016 hasConcept C2778128677 @default.
• W2063587016 hasConcept C2778957662 @default.
• W2063587016 hasConcept C2780854706 @default.
• W2063587016 hasConcept C3675279 @default.
• W2063587016 hasConcept C55493867 @default.
• W2063587016 hasConcept C62231903 @default.
• W2063587016 hasConcept C71315377 @default.
• W2063587016 hasConcept C71924100 @default.
• W2063587016 hasConcept C86803240 @default.
• W2063587016 hasConcept C88099638 @default.
• W2063587016 hasConcept C9506865 @default.
• W2063587016 hasConcept C98335778 @default.
• W2063587016 hasConceptScore W2063587016C101972281 @default.
• W2063587016 hasConceptScore W2063587016C10730799 @default.
• W2063587016 hasConceptScore W2063587016C126322002 @default.
• W2063587016 hasConceptScore W2063587016C134018914 @default.
• W2063587016 hasConceptScore W2063587016C140137476 @default.
• W2063587016 hasConceptScore W2063587016C141359234 @default.
• W2063587016 hasConceptScore W2063587016C181199279 @default.
• W2063587016 hasConceptScore W2063587016C190098323 @default.
• W2063587016 hasConceptScore W2063587016C20251656 @default.
• W2063587016 hasConceptScore W2063587016C20904676 @default.
• W2063587016 hasConceptScore W2063587016C2776317432 @default.
• W2063587016 hasConceptScore W2063587016C2777318727 @default.
• W2063587016 hasConceptScore W2063587016C2778128677 @default.
• W2063587016 hasConceptScore W2063587016C2778957662 @default.
• W2063587016 hasConceptScore W2063587016C2780854706 @default.
• W2063587016 hasConceptScore W2063587016C3675279 @default.
• W2063587016 hasConceptScore W2063587016C55493867 @default.
• W2063587016 hasConceptScore W2063587016C62231903 @default.
• W2063587016 hasConceptScore W2063587016C71315377 @default.
• W2063587016 hasConceptScore W2063587016C71924100 @default.
• W2063587016 hasConceptScore W2063587016C86803240 @default.
• W2063587016 hasConceptScore W2063587016C88099638 @default.
• W2063587016 hasConceptScore W2063587016C9506865 @default.
• W2063587016 hasConceptScore W2063587016C98335778 @default.
• W2063587016 hasIssue "3" @default.
• W2063587016 hasLocation W20635870161 @default.
• W2063587016 hasLocation W20635870162 @default.
• W2063587016 hasOpenAccess W2063587016 @default.
• W2063587016 hasPrimaryLocation W20635870161 @default.
• W2063587016 hasRelatedWork W1983743856 @default.

• next