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• W2063600256 abstract "Multielectrode recordings were used to identify and measure the axonal inputs to each end plate on contiguous surface fibers covering about 25% of the Xenopus pectoralis muscle in mature and developing animals. The mature innervation pattern was remarkably precise. Individual axons tended to innervate fibers of similar input resistance (Rin) in compact motor units restricted to only a portion of the region studied. Motor units comprising fibers of similar Rin overlapped mainly near their borders. Most fibers had two end plates. In more than 80% of these fibers, both end plates received input from the same axon. In 57%, this was the only input to both end plates. This implies a powerful mechanism for excluding or eliminating inputs from other axons. About 16% of the mature junctions showed focal polyneuronal innervation, with the weaker end plate potential component often less than 1 mV in noncurarized preparations. However, we have no evidence that the weaker inputs were being eliminated. During development, motor units became more compact, which was associated with synapse elimination; but from the earliest times studied, soon after metamorphosis when many fibers were adding second end plates, a majority of those that had two end plates were innervated at both sites by the same axon. © 1996 John Wiley & Sons, Inc." @default.
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• W2063600256 date "1996-12-01" @default.
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• W2063600256 title "Specificity and development of innervation pattern ofXenopus pectoralis muscle" @default.
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• W2063600256 doi "https://doi.org/10.1002/(sici)1097-4695(199612)31:4<415::aid-neu3>3.0.co;2-c" @default.
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