Matches in SemOpenAlex for { <https://semopenalex.org/work/W2063621787> ?p ?o ?g. }
Showing items 1 to 76 of
76
with 100 items per page.
- W2063621787 endingPage "129" @default.
- W2063621787 startingPage "127" @default.
- W2063621787 abstract "It has been demonstrated that in various physiological and pathophysiological processes superoxide functions as a signaling molecule by the way different from those mediated by hydrogen peroxide, hydroxyl radicals, or peroxynitrite. However, until now the mechanism of superoxide signaling remains obscure. A well known role of superoxide as a precursor of reactive hydroxyl radicals by the superoxide-dependent Fenton reaction or the formation of peroxynitrite must result in the damage of the target molecules and lead to pathological disorders. However, this mechanism is unlikely in such processes as the stimulation by superoxide of enzymatic phosphorylation and dephosphorylation. But, not being a super-oxidant, superoxide possesses the frequently forgotten super-nucleophilic properties. Now, we propose a new mechanism for superoxide signaling depending on its nucleophilic reactions. Possible nucleophilic mechanisms of superoxide signaling in the hydrolysis of phosphatidylinositol to inositol 1,4,5-tris-phosphate and in the catalysis of phosphorylation by mitogen-activated protein kinases, phospholipase C and other enzymes are considered." @default.
- W2063621787 created "2016-06-24" @default.
- W2063621787 creator A5014501806 @default.
- W2063621787 date "2005-01-01" @default.
- W2063621787 modified "2023-10-17" @default.
- W2063621787 title "On mechanism of superoxide signaling under physiological and pathophysiological conditions" @default.
- W2063621787 cites W1965530345 @default.
- W2063621787 cites W1968529156 @default.
- W2063621787 cites W1978791874 @default.
- W2063621787 cites W1988176697 @default.
- W2063621787 cites W1998067926 @default.
- W2063621787 cites W2014281402 @default.
- W2063621787 cites W2055635848 @default.
- W2063621787 cites W2068994626 @default.
- W2063621787 cites W2070539510 @default.
- W2063621787 cites W2083790949 @default.
- W2063621787 cites W2152300854 @default.
- W2063621787 cites W2159984465 @default.
- W2063621787 cites W2344997735 @default.
- W2063621787 doi "https://doi.org/10.1016/j.mehy.2004.05.009" @default.
- W2063621787 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15533629" @default.
- W2063621787 hasPublicationYear "2005" @default.
- W2063621787 type Work @default.
- W2063621787 sameAs 2063621787 @default.
- W2063621787 citedByCount "30" @default.
- W2063621787 countsByYear W20636217872012 @default.
- W2063621787 countsByYear W20636217872013 @default.
- W2063621787 countsByYear W20636217872014 @default.
- W2063621787 countsByYear W20636217872015 @default.
- W2063621787 countsByYear W20636217872016 @default.
- W2063621787 countsByYear W20636217872017 @default.
- W2063621787 countsByYear W20636217872019 @default.
- W2063621787 countsByYear W20636217872021 @default.
- W2063621787 countsByYear W20636217872022 @default.
- W2063621787 crossrefType "journal-article" @default.
- W2063621787 hasAuthorship W2063621787A5014501806 @default.
- W2063621787 hasConcept C11960822 @default.
- W2063621787 hasConcept C181199279 @default.
- W2063621787 hasConcept C185592680 @default.
- W2063621787 hasConcept C2775838275 @default.
- W2063621787 hasConcept C2778784160 @default.
- W2063621787 hasConcept C2780795997 @default.
- W2063621787 hasConcept C48349386 @default.
- W2063621787 hasConcept C55493867 @default.
- W2063621787 hasConcept C62478195 @default.
- W2063621787 hasConceptScore W2063621787C11960822 @default.
- W2063621787 hasConceptScore W2063621787C181199279 @default.
- W2063621787 hasConceptScore W2063621787C185592680 @default.
- W2063621787 hasConceptScore W2063621787C2775838275 @default.
- W2063621787 hasConceptScore W2063621787C2778784160 @default.
- W2063621787 hasConceptScore W2063621787C2780795997 @default.
- W2063621787 hasConceptScore W2063621787C48349386 @default.
- W2063621787 hasConceptScore W2063621787C55493867 @default.
- W2063621787 hasConceptScore W2063621787C62478195 @default.
- W2063621787 hasIssue "1" @default.
- W2063621787 hasLocation W20636217871 @default.
- W2063621787 hasLocation W20636217872 @default.
- W2063621787 hasOpenAccess W2063621787 @default.
- W2063621787 hasPrimaryLocation W20636217871 @default.
- W2063621787 hasRelatedWork W19970941 @default.
- W2063621787 hasRelatedWork W2015899487 @default.
- W2063621787 hasRelatedWork W2101615077 @default.
- W2063621787 hasRelatedWork W2104989112 @default.
- W2063621787 hasRelatedWork W2171529323 @default.
- W2063621787 hasRelatedWork W2291668107 @default.
- W2063621787 hasRelatedWork W2396059221 @default.
- W2063621787 hasRelatedWork W2416079538 @default.
- W2063621787 hasRelatedWork W59323186 @default.
- W2063621787 hasRelatedWork W130303252 @default.
- W2063621787 hasVolume "64" @default.
- W2063621787 isParatext "false" @default.
- W2063621787 isRetracted "false" @default.
- W2063621787 magId "2063621787" @default.
- W2063621787 workType "article" @default.