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- W2063645083 abstract "Objective: To review the current practice of adolescent health care providers when an adolescent reports a negative or uncertain history of chickenpox in order to provide information for future practice. Methods: Retrospective chart review of a sample of patients seen in a hospital-based adolescent primary care clinic between 1996 and 1999. Results: Among adolescents who reported a positive history of chickenpox (190 patients, aged 15 ± 1 years), varicella occurred before age 5 years in 30%, between 5 and 10 years in 56%, and at older than age 10 years in 14% of the patients. When adolescents reported a negative or uncertain history of varicella (55 patients, aged 15 ± 1 years), serotesting was ordered for the majority (73%) of cases, while only 16% were presumptively vaccinated with varicella vaccine. In six patients no intervention was noted in the charts, and these patients were contacted. In 80% of the patients who were serotested, varicella IgG titers of ≥ 1:32 indicated a previous unnoticed infection and lifelong immunity to varicella. In only 20% of the patients sera were negative for varicella IgG titer, requiring varicella vaccination. There was no statistical difference between the number of siblings of patients with a positive serologic test (3 ± 1) and the number of siblings of seronegative patients (2 ± 1, p = 0.41). Seven of the eight seronegative patients consented to varicella vaccination and were vaccinated within 10 months of serotesting. Conclusions: These data support the practice of serotesting for a previously unnoticed varicella infection rather than presumptive vaccination in the adolescent age group. A follow-up vaccination of seronegative adolescents should be scheduled as close to serotesting as possible." @default.
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- W2063645083 date "2001-01-01" @default.
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- W2063645083 title "Serotesting versus presumptive varicella vaccination of adolescents with a negative or uncertain history of chickenpox" @default.
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- W2063645083 doi "https://doi.org/10.1016/s1054-139x(00)00174-9" @default.
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