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- W2063654491 abstract "Purpose To compare the clinical assessment of fixation preference (FP) to visual acuity (VA) in a population-based sample of preschool children with amblyopia risk factors. Design Evaluation of diagnostic test in a population-based study. Participants Two hundred forty-three children with amblyopia and/or strabismus, aged 30–72 months, living in Los Angeles County, California. Methods Before measuring VA, FP testing was performed at near and usually without correction, using the binocular fixation pattern in children with strabismus >10 prism diopters (Δ), or the induced tropia test for children with strabismus ≤10Δ or without strabismus. We determined the sensitivity and specificity of FP testing for predicting unilateral amblyopia, defined by optotype VA, among children with amblyopia risk factors. Main Outcome Measure Grade of FP. Results Sensitivity of FP testing for amblyopia among children with anisometropia was 20% (9/44) and specificity was 94% (102/109). Among strabismic children, sensitivity was 69% (9/13; worse in children 30–47 than 48–72 months old) and specificity was 79% (70/89), with similar findings for esotropia and exotropia. Conclusion The ability of FP testing to correctly identify amblyopia in preschool children with amblyopia risk factors is poor. Clinicians should be wary of using FP as a surrogate measure of interocular difference in VA in young children. Financial Disclosure(s) The authors have no proprietary or commercial interest in any materials discussed in this article. To compare the clinical assessment of fixation preference (FP) to visual acuity (VA) in a population-based sample of preschool children with amblyopia risk factors. Evaluation of diagnostic test in a population-based study. Two hundred forty-three children with amblyopia and/or strabismus, aged 30–72 months, living in Los Angeles County, California. Before measuring VA, FP testing was performed at near and usually without correction, using the binocular fixation pattern in children with strabismus >10 prism diopters (Δ), or the induced tropia test for children with strabismus ≤10Δ or without strabismus. We determined the sensitivity and specificity of FP testing for predicting unilateral amblyopia, defined by optotype VA, among children with amblyopia risk factors. Grade of FP. Sensitivity of FP testing for amblyopia among children with anisometropia was 20% (9/44) and specificity was 94% (102/109). Among strabismic children, sensitivity was 69% (9/13; worse in children 30–47 than 48–72 months old) and specificity was 79% (70/89), with similar findings for esotropia and exotropia. The ability of FP testing to correctly identify amblyopia in preschool children with amblyopia risk factors is poor. Clinicians should be wary of using FP as a surrogate measure of interocular difference in VA in young children." @default.
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- W2063654491 date "2009-01-01" @default.
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- W2063654491 title "Fixation Preference and Visual Acuity Testing in a Population-based Cohort of Preschool Children with Amblyopia Risk Factors" @default.
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- W2063654491 doi "https://doi.org/10.1016/j.ophtha.2008.08.031" @default.
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