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- W2063659513 abstract "Abstract IgG 1 induction factor elevates the IgG l response induced by lipopolysaccharide and suppresses the lipopolysaccharide‐induced IgG 3 and IgG Zb responses in cultures of mouse spleen cells. We have developed new T cell lines secreting this factor by cloning mixed lymphocyte culture populations. Using supernatants of one of these T cell lines it was found that the assay is quantitative, reproducible and accurate, both when induction of IgG l as well as reduction of IgG 3 and IgG 2b were measured. Using this analysis, different conditions to induce maximal production of the factor were tested. The cell line was thereafter used as fusion partner with a T cell lymphoma. The hybrids were selected in the presence of T cell growth factor and all of them secreted IgG l induction factor." @default.
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- W2063659513 date "1985-01-01" @default.
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- W2063659513 title "Secretion of IgG1 induction factor by T cell clones and hybridomas" @default.
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- W2063659513 doi "https://doi.org/10.1002/eji.1830150611" @default.
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