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• W2063662382 abstract "Currently, investigations of biomechanical properties of the fibrous tunic are becoming even more topical, especially for diagnosis of corneal ectatic disease, as well as correct interpretation of intraocular pressure (IOP) parameters, particularly in patients with prior surgery on cornea. The study principle is based on the ability of substances to change optical anisotropy depending on mechanical strain applied to them. An experimental set-up was constructed which allows assessment of polarization degree of light which is emitted during luminescence of strained collagen. The study was performed on 18 corneoscleral discs of chinchilla rabbit eyes at 15 and 50mm Hg pressure, among them in 6 cases before and after making radial incisions, and in 6 cases before and after conducting the mechanical cornea abrasions that were asymmetrical by depth until reaching the local zone of iatrogenic keratectasia. Corneal collagen mechanical strain mappings were formed on 3 experimental models (intact cornea, cornea post radial keratotomy and keratectasia) under intra-chamber pressure of 15 and 50mm Hg. Corneal collagen mechanical strain is evenly allocated in the intact cornea. After radial keratotomy the main mechanical loading was concentrated over the middle part of corneal periphery, particularly in the bottom of keratotomic incisions. The increased intra-chamber pressure made the strain rise in those models. Upon cornea abrasion the main straining is distributed within the thinning zone, and the increase of intra-chamber pressure only increases the load over residual stroma. A new principle of corneal biomechanical properties investigation based on assessment of degree of light polarization emitted during luminescence of strained collagen, has been proposed and experimentally tested." @default.
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• W2063662382 date "2013-06-01" @default.
• W2063662382 modified "2023-09-27" @default.
• W2063662382 title "Experimental study on the mechanical strain of corneal collagen" @default.
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• W2063662382 doi "https://doi.org/10.1016/j.jbiomech.2013.04.008" @default.
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