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- W2063670461 abstract "A preliminary pharmacological study of a thiophene analogue 1b of the analgesic and antipyretic agent Ethenzamide and of a closely related compound 1a showed that a great similarity exists among Ethenzamide and the thiophenic compounds for analgesic, antipyretic, ulcerogenic, hypothermic, and sedative effects. However, the acute toxicity in mice for the thiophenic compounds is notably higher than that of Ethenzamide. Synthese und vorläufige pharmakologische Untersuchung der Thiophen-Analoga der antipyretisch und analgetisch wirksamen Verbindung Ethenzamid Eine vorläufige pharmakologische Untersuchung der Thiophen-Analoga 1b des Analgetikums und Antipyretikums Ethenzamid und seines nahen Verwandten 1a zeigte eine große Ähnlichkeit in der analgetischen, antipyretischen, hypothermischen, ulzerogenen und sedativen Wirkung dieser beiden Substanzgruppen. Dem gegenüber war die akute Toxizität bei der Maus für die Thiophen-Verbindungen beträchtlich höher als die des Ethenzamids." @default.
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- W2063670461 date "1992-01-01" @default.
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- W2063670461 title "Synthesis and Preliminary Pharmacological Study of Thiophene Analogues of the Antipyretic and Analgesic Agent Ethenzamide" @default.
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- W2063670461 doi "https://doi.org/10.1002/ardp.19923250206" @default.
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