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Matches in SemOpenAlex for { <https://semopenalex.org/work/W2063700078> ?p ?o ?g. }

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• W2063700078 abstract "From a high-throughput screening (HTS) hit with inhibitory activity against virus-induced cytophathic in the low micromolar range, we have developed a potent anti-influenza lead through careful optimization without compromising the drug-like properties of the compound. An orally bioavailable compound was identified as a lead agent with nanomolar activity against influenza, representing a 140-fold improvement over the initial hit." @default.
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• W2063700078 date "2012-07-23" @default.
• W2063700078 modified "2023-10-12" @default.
• W2063700078 title "Anti-influenza Drug Discovery: Identification of an Orally Bioavailable Quinoline Derivative through Activity- and Property-Guided Lead Optimization" @default.
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• W2063700078 doi "https://doi.org/10.1002/cmdc.201200259" @default.
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