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- W2063732411 abstract "PRL levels were evaluated during long-term treatment with cyproterone acetate 100 mg and ethinyloestradiol 100 μg/day orally or depot-oestrogens in 214 male-to-female transsexuals. PRL levels increased above normal in all subjects (normal < 300 mU/l). In 46 (21.4%) subjects PRL levels rose to > 1000 mU/l. The incidence of PRL levels > 1000 mU/l was 3.7–7.2% per treatment year. Grossly elevated PRL levels were associated with high doses of oestrogens (P < 0.05) and advanced age at the start of treatment (P < 0.05). In 23 subjects PRL levels > 1000 mU/l decreased by more than 50% spontaneously (n= 5) or after dose reduction (n= 18). In five of the subgroup of 15 subjects with persistent PRL levels > 1000 mU/l enlargement of the pituitary gland was shown by CT-scanning. These data suggest that the lowest possible oestrogen dose and lifelong follow-up of hormone-treated male-to-female transsexuals is essential." @default.
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- W2063732411 date "1988-06-01" @default.
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- W2063732411 title "PROLACTIN LEVELS AND PITUITARY ENLARGEMENT IN HORMONE-TREATED MALE-TO-FEMALE TRANSSEXUALS" @default.
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- W2063732411 doi "https://doi.org/10.1111/j.1365-2265.1988.tb03849.x" @default.
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