Matches in SemOpenAlex for { <https://semopenalex.org/work/W2063740475> ?p ?o ?g. }
Showing items 1 to 82 of
82
with 100 items per page.
- W2063740475 endingPage "296" @default.
- W2063740475 startingPage "289" @default.
- W2063740475 abstract "Fasting bile acids in serum of eight children with the syndrome of hepatic ductular hypoplasia were analyzed by gas chromatography. The children did not receive any kind of treatment during the month before the analysis. Serum concentrations of total bile acids ranged from 110.8-303.7 mumol/1. The predominant bile acids were chenodeoxycholic and cholic acids accounting for 62.8-86.5% of the total. The ratio of cholic acid to chenodeoxycholic acid ranged between 0.43 and 1.11. Monohydroxylated bile acids were found in increased amounts in all patients (5.1-23.9%), 3 beta-hydroxy-5-cholenoic acid being the major monohydroxylated bile acid (3.1-17.1%). Other unusual bile acids such as ursodeoxycholic acid and 12-oxo-3 alpha, 7 alpha-dihydroxy-5 beta-cholanoic acid (7.3-14.9%) were also detected. Neither 3 beta-hydroxy-5-cholenoic nor lithocholic acid levels were statistically correlated to cholic or chenodeoxycholic acids. However, a statistically significant correlation between total bile acid levels and 12-oxo-3 alpha, 7 alpha-dihydroxy-5 beta-cholanoic acid levels was found. These findings are interesting as far as the origin of the unusual bile acids found in this cholestatic syndrome is concerned. The large amounts of 3 beta-hydroxy-5-cholenoic acid measured in children with the syndrome of hepatic ductular hypoplasia could indicate the existence of an alternative fetal pathway of bile acid synthesis." @default.
- W2063740475 created "2016-06-24" @default.
- W2063740475 creator A5024721089 @default.
- W2063740475 creator A5031998808 @default.
- W2063740475 creator A5044035250 @default.
- W2063740475 creator A5079458676 @default.
- W2063740475 date "1985-02-01" @default.
- W2063740475 modified "2023-09-25" @default.
- W2063740475 title "Unusual serum bile acid pattern in children with the syndrome of hepatic ductular hypoplasia" @default.
- W2063740475 cites W1672993705 @default.
- W2063740475 cites W1965972971 @default.
- W2063740475 cites W2018314238 @default.
- W2063740475 cites W2019067900 @default.
- W2063740475 cites W2023306652 @default.
- W2063740475 cites W2037805762 @default.
- W2063740475 cites W2038120179 @default.
- W2063740475 cites W2040947899 @default.
- W2063740475 cites W2045585930 @default.
- W2063740475 cites W2049016611 @default.
- W2063740475 cites W2050064627 @default.
- W2063740475 cites W2064368190 @default.
- W2063740475 cites W2074936555 @default.
- W2063740475 cites W2086155268 @default.
- W2063740475 cites W2119455449 @default.
- W2063740475 cites W2140748591 @default.
- W2063740475 cites W2141979812 @default.
- W2063740475 cites W2157942891 @default.
- W2063740475 cites W2469297943 @default.
- W2063740475 doi "https://doi.org/10.1016/0009-8981(85)90036-1" @default.
- W2063740475 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3987031" @default.
- W2063740475 hasPublicationYear "1985" @default.
- W2063740475 type Work @default.
- W2063740475 sameAs 2063740475 @default.
- W2063740475 citedByCount "4" @default.
- W2063740475 countsByYear W20637404752020 @default.
- W2063740475 crossrefType "journal-article" @default.
- W2063740475 hasAuthorship W2063740475A5024721089 @default.
- W2063740475 hasAuthorship W2063740475A5031998808 @default.
- W2063740475 hasAuthorship W2063740475A5044035250 @default.
- W2063740475 hasAuthorship W2063740475A5079458676 @default.
- W2063740475 hasConcept C126322002 @default.
- W2063740475 hasConcept C134018914 @default.
- W2063740475 hasConcept C185592680 @default.
- W2063740475 hasConcept C2775900799 @default.
- W2063740475 hasConcept C2779399885 @default.
- W2063740475 hasConcept C2780420665 @default.
- W2063740475 hasConcept C2780965833 @default.
- W2063740475 hasConcept C2781089062 @default.
- W2063740475 hasConcept C55493867 @default.
- W2063740475 hasConcept C71924100 @default.
- W2063740475 hasConceptScore W2063740475C126322002 @default.
- W2063740475 hasConceptScore W2063740475C134018914 @default.
- W2063740475 hasConceptScore W2063740475C185592680 @default.
- W2063740475 hasConceptScore W2063740475C2775900799 @default.
- W2063740475 hasConceptScore W2063740475C2779399885 @default.
- W2063740475 hasConceptScore W2063740475C2780420665 @default.
- W2063740475 hasConceptScore W2063740475C2780965833 @default.
- W2063740475 hasConceptScore W2063740475C2781089062 @default.
- W2063740475 hasConceptScore W2063740475C55493867 @default.
- W2063740475 hasConceptScore W2063740475C71924100 @default.
- W2063740475 hasIssue "3" @default.
- W2063740475 hasLocation W20637404751 @default.
- W2063740475 hasLocation W20637404752 @default.
- W2063740475 hasOpenAccess W2063740475 @default.
- W2063740475 hasPrimaryLocation W20637404751 @default.
- W2063740475 hasRelatedWork W1610781402 @default.
- W2063740475 hasRelatedWork W2058565396 @default.
- W2063740475 hasRelatedWork W2102818798 @default.
- W2063740475 hasRelatedWork W2147068566 @default.
- W2063740475 hasRelatedWork W2168975531 @default.
- W2063740475 hasRelatedWork W2322434720 @default.
- W2063740475 hasRelatedWork W2343604647 @default.
- W2063740475 hasRelatedWork W2353904832 @default.
- W2063740475 hasRelatedWork W2987963912 @default.
- W2063740475 hasRelatedWork W2007350600 @default.
- W2063740475 hasVolume "145" @default.
- W2063740475 isParatext "false" @default.
- W2063740475 isRetracted "false" @default.
- W2063740475 magId "2063740475" @default.
- W2063740475 workType "article" @default.