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W2063744211 abstract "The seeds of Jatropha curcas L. ingested accidentally by two children aged 3 and 5 years led to a clinical syndrome of restlessness, severe vomiting and dehydration. A systematic study of the seeds indicated that they produced toxic effects in mice. Macroscopic anal haemorrhage and death occurred when the seeds were administered with the feed. Post-mortem examination revealed infarction of various parts of the gatrointestinal tract with congested vessels. Sodium chloride solution (150 mmol/l: saline) extract of the dried seed administered intraperitoneally into mice caused death in doses as low as 1 mg/kg. Post-mortem studies in this case showed widespread haemorrhages involving the colon, lungs as well as infarction of the liver. Larger intraperitoneal doses (> 30 mg/kg) were lethal rapidly but not associated with gross gastrointestinal haemorrhage." @default.
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W2063744211 date "1986-07-01" @default.
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W2063744211 title "Acute Toxicity Studies with Jatropha curcas L" @default.
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W2063744211 doi "https://doi.org/10.1177/096032718600500409" @default.
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