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- W2063774669 abstract "Dissociated cells (mainly neuroblasts) obtained from brain hemispheres of chick embryos adhere to a preformed layer of chick brain astroglial cells faster and to a greater extent than to a layer of chick fibroblasts. At the begining of the experiment the adhered neuroblasts are dispersed on both layers but within a short time neuroblasts on a fibroblast layer migrate, form clusters and only later on begin to differentiate; in contrast those on an astroglial layer remain dispersed and differentiate rapidly. In both cases a number of cells of each inoculum do not adhere to either cellular layer, but these cells do not differ morphologically from those which adhered. Adhesion of neuroblasts to astroglial layers and that to fibroblast layers appear to follow the kinetics of an irreversible one-step reaction in pseudo-first-order conditions only for the first 50 and 60 min respectively. The departure from linearity of the kinetics after these times does not correspond, however, to the occurrence of second-order conditions. Other possible mechanisms of adhesion which could explain the experimental data are compared with those expected for different kinetic mechanisms. A model in which cell adhesion is treated in terms of affinity between receptor and ligands is used to analyse the nature of cell-cell adhesion." @default.
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- W2063774669 date "1982-02-01" @default.
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- W2063774669 title "Kinetic and morphological analysis of the preferential adhesion of chick embryo neuronal cells to astroglial cells in culture" @default.
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- W2063774669 doi "https://doi.org/10.1016/0014-4827(82)90029-5" @default.
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