Matches in SemOpenAlex for { <https://semopenalex.org/work/W2063784711> ?p ?o ?g. }
- W2063784711 endingPage "48" @default.
- W2063784711 startingPage "37" @default.
- W2063784711 abstract "Culturally driven marital practices provide a key instance of an interaction between social and genetic processes in shaping patterns of human genetic variation, producing, for example, increased identity by descent through consanguineous marriage. A commonly used measure to quantify identity by descent in an individual is the inbreeding coefficient, a quantity that reflects not only consanguinity, but also other aspects of kinship in the population to which the individual belongs. Here, in populations worldwide, we examine the relationship between genomic estimates of the inbreeding coefficient and population patterns in genetic variation.Using genotypes at 645 microsatellites, we compare inbreeding coefficients from 5,043 individuals representing 237 populations worldwide to demographic consanguinity frequency estimates available for 26 populations as well as to other quantities that can illuminate population-genetic influences on inbreeding coefficients.We observe higher inbreeding coefficient estimates in populations and geographic regions with known high levels of consanguinity or genetic isolation and in populations with an increased effect of genetic drift and decreased genetic diversity with increasing distance from Africa. For the small number of populations with specific consanguinity estimates, we find a correlation between inbreeding coefficients and consanguinity frequency (r = 0.349, p = 0.040).The results emphasize the importance of both consanguinity and population-genetic factors in influencing variation in inbreeding coefficients, and they provide insight into factors useful for assessing the effect of consanguinity on genomic patterns in different populations." @default.
- W2063784711 created "2016-06-24" @default.
- W2063784711 creator A5013539361 @default.
- W2063784711 creator A5052136772 @default.
- W2063784711 date "2014-01-01" @default.
- W2063784711 modified "2023-10-13" @default.
- W2063784711 title "Population-Genetic Influences on Genomic Estimates of the Inbreeding Coefficient: A Global Perspective" @default.
- W2063784711 cites W101716102 @default.
- W2063784711 cites W1512844375 @default.
- W2063784711 cites W1608919626 @default.
- W2063784711 cites W1889661195 @default.
- W2063784711 cites W1924757566 @default.
- W2063784711 cites W1939346899 @default.
- W2063784711 cites W1941414266 @default.
- W2063784711 cites W1964938039 @default.
- W2063784711 cites W1968194187 @default.
- W2063784711 cites W1971613680 @default.
- W2063784711 cites W1977334844 @default.
- W2063784711 cites W1977597564 @default.
- W2063784711 cites W1978412436 @default.
- W2063784711 cites W1978553454 @default.
- W2063784711 cites W1980927228 @default.
- W2063784711 cites W1981821647 @default.
- W2063784711 cites W1984046516 @default.
- W2063784711 cites W1992700573 @default.
- W2063784711 cites W1993867652 @default.
- W2063784711 cites W1994193335 @default.
- W2063784711 cites W1995796724 @default.
- W2063784711 cites W1997476591 @default.
- W2063784711 cites W1997722194 @default.
- W2063784711 cites W1998667996 @default.
- W2063784711 cites W1999277251 @default.
- W2063784711 cites W2006115852 @default.
- W2063784711 cites W2010447172 @default.
- W2063784711 cites W2014659703 @default.
- W2063784711 cites W2017855669 @default.
- W2063784711 cites W2018828902 @default.
- W2063784711 cites W2020302614 @default.
- W2063784711 cites W2022939902 @default.
- W2063784711 cites W2023291869 @default.
- W2063784711 cites W2028151581 @default.
- W2063784711 cites W2032301833 @default.
- W2063784711 cites W2032778435 @default.
- W2063784711 cites W2038385776 @default.
- W2063784711 cites W2041007883 @default.
- W2063784711 cites W2045658286 @default.
- W2063784711 cites W2050058649 @default.
- W2063784711 cites W2052363378 @default.
- W2063784711 cites W2052923237 @default.
- W2063784711 cites W2054923113 @default.
- W2063784711 cites W2055485782 @default.
- W2063784711 cites W2056494169 @default.
- W2063784711 cites W2059143188 @default.
- W2063784711 cites W2063026409 @default.
- W2063784711 cites W2074421594 @default.
- W2063784711 cites W2075190118 @default.
- W2063784711 cites W2078287875 @default.
- W2063784711 cites W2083287967 @default.
- W2063784711 cites W2083390520 @default.
- W2063784711 cites W2096826261 @default.
- W2063784711 cites W2102126823 @default.
- W2063784711 cites W2104949710 @default.
- W2063784711 cites W2108434896 @default.
- W2063784711 cites W2111401476 @default.
- W2063784711 cites W2114325165 @default.
- W2063784711 cites W2116233894 @default.
- W2063784711 cites W2119799171 @default.
- W2063784711 cites W2120767159 @default.
- W2063784711 cites W2122754674 @default.
- W2063784711 cites W2129316818 @default.
- W2063784711 cites W2132656211 @default.
- W2063784711 cites W2134049753 @default.
- W2063784711 cites W2141810183 @default.
- W2063784711 cites W2144890473 @default.
- W2063784711 cites W2148519154 @default.
- W2063784711 cites W2148524904 @default.
- W2063784711 cites W2154486937 @default.
- W2063784711 cites W2157535960 @default.
- W2063784711 cites W2157659569 @default.
- W2063784711 cites W2161633633 @default.
- W2063784711 cites W2162372514 @default.
- W2063784711 cites W2164254602 @default.
- W2063784711 cites W2165020864 @default.
- W2063784711 cites W2167450142 @default.
- W2063784711 cites W2167651190 @default.
- W2063784711 cites W2171655976 @default.
- W2063784711 cites W2315840333 @default.
- W2063784711 cites W2401404747 @default.
- W2063784711 cites W2414762610 @default.
- W2063784711 cites W2418613197 @default.
- W2063784711 cites W2438995858 @default.
- W2063784711 cites W2503045181 @default.
- W2063784711 cites W2797702512 @default.
- W2063784711 cites W33196722 @default.
- W2063784711 cites W346665861 @default.
- W2063784711 cites W354944978 @default.
- W2063784711 cites W93412799 @default.
- W2063784711 cites W93588716 @default.