Matches in SemOpenAlex for { <https://semopenalex.org/work/W2063788891> ?p ?o ?g. }
Showing items 1 to 87 of
87
with 100 items per page.
- W2063788891 endingPage "126" @default.
- W2063788891 startingPage "121" @default.
- W2063788891 abstract "In three patients whose Guillain-Barré syndrome (GBS) was preceded by gastrointestinal infection due to Campylobacter jejuni, gammadelta T cells were generated from peripheral blood in response to in vitro stimulation with C. jejuni. In one of the patients, where a diagnostic sural nerve biopsy was performed, gammadelta T cells were also isolated following culture of the nerve tissue. Studies with healthy volunteers and C. jejuni gastroenteritis patients also showed preferential enrichment for gammadelta T cells in peripheral blood cells stimulated with C. jejuni, although the response was significantly lower than that seen in GBS patients. In two out of three GBS patients and all of the controls, gammadelta T cell receptor (TCR) gene usage was shown to be Vgamma9/Vdelta2+. In the GBS patient where nerve-infiltrating gammadelta T cells were isolated, these and C. jejuni-specific peripheral blood cells had similar TCR gene usage, predominantly consisting of Vgamma5/Vdelta1+ cells. Sequencing the Vdelta1 products from nerve and peripheral blood showed similarities in CDR3 length, but the single Vdelta1 sequence obtained from nerve was not identified in peripheral blood. These results suggest that the generation of gammadelta T cells is part of a normal immune response to C. jejuni, which, in patients with GBS, may contribute to the pathogenesis of their inflammatory neuropathy." @default.
- W2063788891 created "2016-06-24" @default.
- W2063788891 creator A5055139683 @default.
- W2063788891 creator A5068429951 @default.
- W2063788891 creator A5069787627 @default.
- W2063788891 creator A5090346729 @default.
- W2063788891 date "1997-07-01" @default.
- W2063788891 modified "2023-10-13" @default.
- W2063788891 title "Stimulation of peripheral blood lymphocytes with <i>Campylobacter jejuni</i> generates a γδ T cell response in patients with Guillain–Barré syndrome" @default.
- W2063788891 cites W1896605459 @default.
- W2063788891 cites W1955068511 @default.
- W2063788891 cites W1966788249 @default.
- W2063788891 cites W1997283465 @default.
- W2063788891 cites W2034318072 @default.
- W2063788891 cites W2034607893 @default.
- W2063788891 cites W2037569685 @default.
- W2063788891 cites W2044284260 @default.
- W2063788891 cites W2055016844 @default.
- W2063788891 cites W2099889645 @default.
- W2063788891 cites W2104106789 @default.
- W2063788891 cites W2145938766 @default.
- W2063788891 cites W2147448294 @default.
- W2063788891 cites W2153778599 @default.
- W2063788891 cites W2179539455 @default.
- W2063788891 cites W2313469424 @default.
- W2063788891 cites W2337049506 @default.
- W2063788891 cites W2398609420 @default.
- W2063788891 doi "https://doi.org/10.1046/j.1365-2249.1997.4221318.x" @default.
- W2063788891 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1904723" @default.
- W2063788891 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9218834" @default.
- W2063788891 hasPublicationYear "1997" @default.
- W2063788891 type Work @default.
- W2063788891 sameAs 2063788891 @default.
- W2063788891 citedByCount "31" @default.
- W2063788891 countsByYear W20637888912016 @default.
- W2063788891 countsByYear W20637888912018 @default.
- W2063788891 countsByYear W20637888912021 @default.
- W2063788891 countsByYear W20637888912023 @default.
- W2063788891 crossrefType "journal-article" @default.
- W2063788891 hasAuthorship W2063788891A5055139683 @default.
- W2063788891 hasAuthorship W2063788891A5068429951 @default.
- W2063788891 hasAuthorship W2063788891A5069787627 @default.
- W2063788891 hasAuthorship W2063788891A5090346729 @default.
- W2063788891 hasBestOaLocation W20637888911 @default.
- W2063788891 hasConcept C19317047 @default.
- W2063788891 hasConcept C203014093 @default.
- W2063788891 hasConcept C2776090121 @default.
- W2063788891 hasConcept C2776957140 @default.
- W2063788891 hasConcept C2778691916 @default.
- W2063788891 hasConcept C523546767 @default.
- W2063788891 hasConcept C54355233 @default.
- W2063788891 hasConcept C71924100 @default.
- W2063788891 hasConcept C86803240 @default.
- W2063788891 hasConcept C8891405 @default.
- W2063788891 hasConceptScore W2063788891C19317047 @default.
- W2063788891 hasConceptScore W2063788891C203014093 @default.
- W2063788891 hasConceptScore W2063788891C2776090121 @default.
- W2063788891 hasConceptScore W2063788891C2776957140 @default.
- W2063788891 hasConceptScore W2063788891C2778691916 @default.
- W2063788891 hasConceptScore W2063788891C523546767 @default.
- W2063788891 hasConceptScore W2063788891C54355233 @default.
- W2063788891 hasConceptScore W2063788891C71924100 @default.
- W2063788891 hasConceptScore W2063788891C86803240 @default.
- W2063788891 hasConceptScore W2063788891C8891405 @default.
- W2063788891 hasIssue "1" @default.
- W2063788891 hasLocation W20637888911 @default.
- W2063788891 hasLocation W20637888912 @default.
- W2063788891 hasLocation W20637888913 @default.
- W2063788891 hasOpenAccess W2063788891 @default.
- W2063788891 hasPrimaryLocation W20637888911 @default.
- W2063788891 hasRelatedWork W2007615535 @default.
- W2063788891 hasRelatedWork W2012972418 @default.
- W2063788891 hasRelatedWork W2018104302 @default.
- W2063788891 hasRelatedWork W2026444950 @default.
- W2063788891 hasRelatedWork W2040128205 @default.
- W2063788891 hasRelatedWork W2060075608 @default.
- W2063788891 hasRelatedWork W2122619091 @default.
- W2063788891 hasRelatedWork W2168929838 @default.
- W2063788891 hasRelatedWork W3137013119 @default.
- W2063788891 hasRelatedWork W4242688910 @default.
- W2063788891 hasVolume "109" @default.
- W2063788891 isParatext "false" @default.
- W2063788891 isRetracted "false" @default.
- W2063788891 magId "2063788891" @default.
- W2063788891 workType "article" @default.