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• W2063826908 abstract "Although chronic hepatitis C (CH-C) has consistently been shown to impair patients' health-related quality of life (HRQL), the impact of chronic hepatitis B (CH-B) on HRQL has not been fully explored.Compare HRQL between patients with CH-B, CH-C, primary biliary cirrhosis (PBC) and healthy controls.Three HRQL questionnaires [Chronic Liver Disease Questionnaire (CLDQ), Short Form 36 (SF-36) and the Health Utility Index (HUI Mark-2 and Mark-3)] were administered prospectively. Additional clinical and laboratory data and normative data for healthy individuals, were available.Scores were compared using analysis of variance and multiple regression.One hundred and forty-six patients with CH-B, CH-C and PBC were included [mean age 47.1 years (+/-11.6), 41% female, 33% cirrhosis]. CH-C and PBC patients scored the lowest on all CLDQ, SF-36 and HUI domains compared with CH-B patients and healthy controls. CH-B patients had scores similar to the healthy population, measured by most CLDQ and SF-36 scales. However, the HUI scores for CH-B patients showed more impairment than population norms. Having CH-B and not having cirrhosis were predictive of utility and HRQL scores in multivariate models.CH-B patients have better HRQL than CH-C, PBC and population norms. CH-B patients' overall utility scores are lower than population norms." @default.
• W2063826908 created "2016-06-24" @default.
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• W2063826908 date "2007-10-01" @default.
• W2063826908 modified "2023-10-10" @default.
• W2063826908 title "Health-related quality of life in patients with chronic hepatitis B" @default.
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• W2063826908 doi "https://doi.org/10.1111/j.1478-3231.2007.01558.x" @default.
• W2063826908 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17845541" @default.
• W2063826908 hasPublicationYear "2007" @default.
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