FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2063856596> ?p ?o ?g. }

• W2063856596 endingPage "e201210002" @default.
• W2063856596 startingPage "e201210002" @default.
• W2063856596 abstract "The hemoglobin (VHb) from Vitreoscilla was the first bacterial hemoglobin discovered. Its structure and function have been extensively investigated, and engineering of a wide variety of heterologous organisms to express VHb has been performed to increase their growth and productivity. This strategy has shown promise in applications as far-ranging as the production of antibiotics and petrochemical replacements by microorganisms to increasing stress tolerance in plants. These applications of VHb technology have generally been of the black box variety, wherein the endpoint studied is an increase in the levels of a certain product or improved growth and survival. Their eventual optimization, however, will require a thorough understanding of the various functions and activities of VHb, and how VHb expression ripples to affect metabolism more generally. Here we review the current knowledge of these topics. VHb's functions all involve oxygen binding (and often delivery) in one way or another. Several biochemical and structure-function studies have provided an insight into the molecular details of this binding and delivery. VHb activities are varied. They include supply of oxygen to oxygenases and the respiratory chain, particularly under low oxygen conditions; oxygen sensing and modulation of transcription factor activity; and detoxification of NO, and seem to require interactions of VHb with partner proteins. VHb expression affects the levels of ATP and NADH, although not enormously. VHb expression may affect the level of many compounds of intermediary metabolism, and, apparently, alters the levels of expression of many genes. Thus, the metabolic changes in organisms engineered to express VHb are likely to be numerous and complicated." @default.
• W2063856596 created "2016-06-24" @default.
• W2063856596 creator A5002752327 @default.
• W2063856596 creator A5066733001 @default.
• W2063856596 creator A5073478356 @default.
• W2063856596 date "2012-10-01" @default.
• W2063856596 modified "2023-09-27" @default.
• W2063856596 title "THE BIOCHEMISTRY OF VITREOSCILLA HEMOGLOBIN" @default.
• W2063856596 cites W1486097395 @default.
• W2063856596 cites W1496345318 @default.
• W2063856596 cites W1514138614 @default.
• W2063856596 cites W1520725245 @default.
• W2063856596 cites W1567843894 @default.
• W2063856596 cites W1599275850 @default.
• W2063856596 cites W1681899478 @default.
• W2063856596 cites W1965073965 @default.
• W2063856596 cites W1965266053 @default.
• W2063856596 cites W1966532708 @default.
• W2063856596 cites W1967987135 @default.
• W2063856596 cites W1972539459 @default.
• W2063856596 cites W1976667938 @default.
• W2063856596 cites W1978677359 @default.
• W2063856596 cites W1986334735 @default.
• W2063856596 cites W1989876146 @default.
• W2063856596 cites W1992835908 @default.
• W2063856596 cites W2006365085 @default.
• W2063856596 cites W2012061325 @default.
• W2063856596 cites W2013242407 @default.
• W2063856596 cites W2013875876 @default.
• W2063856596 cites W2019180305 @default.
• W2063856596 cites W2020923737 @default.
• W2063856596 cites W2021806597 @default.
• W2063856596 cites W2023846875 @default.
• W2063856596 cites W2033926380 @default.
• W2063856596 cites W2036257596 @default.
• W2063856596 cites W2036359124 @default.
• W2063856596 cites W2039208542 @default.
• W2063856596 cites W2040163876 @default.
• W2063856596 cites W2041321422 @default.
• W2063856596 cites W2044334990 @default.
• W2063856596 cites W2049162867 @default.
• W2063856596 cites W2050793888 @default.
• W2063856596 cites W2054109525 @default.
• W2063856596 cites W2058849821 @default.
• W2063856596 cites W2059612429 @default.
• W2063856596 cites W2062134719 @default.
• W2063856596 cites W2063833044 @default.
• W2063856596 cites W2069848230 @default.
• W2063856596 cites W2069891698 @default.
• W2063856596 cites W2074320176 @default.
• W2063856596 cites W2075798680 @default.
• W2063856596 cites W2075813903 @default.
• W2063856596 cites W2081337483 @default.
• W2063856596 cites W2082932004 @default.
• W2063856596 cites W2084659943 @default.
• W2063856596 cites W2089075419 @default.
• W2063856596 cites W2090775573 @default.
• W2063856596 cites W2090835951 @default.
• W2063856596 cites W2104666616 @default.
• W2063856596 cites W2117354621 @default.
• W2063856596 cites W2119055464 @default.
• W2063856596 cites W2120024755 @default.
• W2063856596 cites W2124304921 @default.
• W2063856596 cites W2130746911 @default.
• W2063856596 cites W2131499356 @default.
• W2063856596 cites W2132505334 @default.
• W2063856596 cites W2133709520 @default.
• W2063856596 cites W2143731004 @default.
• W2063856596 cites W2146789938 @default.
• W2063856596 cites W2156623223 @default.
• W2063856596 cites W2160870641 @default.
• W2063856596 cites W2168467184 @default.
• W2063856596 cites W2280846210 @default.
• W2063856596 cites W242359278 @default.
• W2063856596 cites W2431721080 @default.
• W2063856596 cites W4247631748 @default.
• W2063856596 cites W84298937 @default.
• W2063856596 cites W88404120 @default.
• W2063856596 doi "https://doi.org/10.5936/csbj.201210002" @default.
• W2063856596 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3962134" @default.
• W2063856596 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24688662" @default.
• W2063856596 hasPublicationYear "2012" @default.
• W2063856596 type Work @default.
• W2063856596 sameAs 2063856596 @default.
• W2063856596 citedByCount "29" @default.
• W2063856596 countsByYear W20638565962014 @default.
• W2063856596 countsByYear W20638565962015 @default.
• W2063856596 countsByYear W20638565962016 @default.
• W2063856596 countsByYear W20638565962017 @default.
• W2063856596 countsByYear W20638565962018 @default.
• W2063856596 countsByYear W20638565962019 @default.
• W2063856596 countsByYear W20638565962020 @default.
• W2063856596 countsByYear W20638565962021 @default.
• W2063856596 countsByYear W20638565962022 @default.
• W2063856596 countsByYear W20638565962023 @default.
• W2063856596 crossrefType "journal-article" @default.
• W2063856596 hasAuthorship W2063856596A5002752327 @default.
• W2063856596 hasAuthorship W2063856596A5066733001 @default.

• next