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- W2063876039 abstract "Genetic haemochromatosis (GH) is one of the commonest inherited disorders, with a frequency of 0.4–1.0% in people of northern European origin. Affected individuals absorb excessive amounts of iron from the gut, leading to iron deposition (siderosis) in many internal organs. Clinical manifestations mainly relate to hepatic, cardiac and pancreatic disease. Complications of liver disease include progressive fibrosis leading to cirrhosis and hepatocellular carcinoma, and these are the main cause of death in patients with GH. Fibrosis is also a feature of iron overload in the pancreas and heart." @default.
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- W2063876039 date "2003-04-01" @default.
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- W2063876039 title "Iron overload, inflammation and fibrosis in genetic haemochromatosis" @default.
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- W2063876039 doi "https://doi.org/10.1016/s0168-8278(03)00078-3" @default.
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