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- W2063879439 abstract "N6-Cyclohexyl-[3H]adenosine [( 3H]CHA) binds specifically to rat brain membranes prepared from the caudate-putamen complex with a Kd value of 2.50 +/- 0.39 nM and Bmax of 458 +/- 51 fmol/mg protein. Lesioning the nigrostriatal dopaminergic pathway using 6-hydroxydopamine failed to alter [3H]CHA binding characteristics. Intrastriatal kainate lesions reduced the binding capacity of [3H]CHA by 28% though this was not statistically significant (0.1 less than P greater than 0.05). In kainate-lesioned striata, however, 2-deoxyglucose uptake was reduced by only 39%." @default.
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- W2063879439 date "1985-05-01" @default.
- W2063879439 modified "2023-09-25" @default.
- W2063879439 title "Cyclohexyladenosine binding in rat striatum" @default.
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- W2063879439 doi "https://doi.org/10.1016/0006-8993(85)90238-0" @default.
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