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• W2063889189 abstract "4,5-Dihyroxypyrimidine carboxamides, which evolved from a related series of HCV NS5b polymerase inhibitors, have been optimized to provide selective HIV integrase strand transfer inhibitors. Extensive SAR around the benzylamide moiety led to the identification of the p-fluorobenzylamide as optimal in the enzymatic assay." @default.
• W2063889189 created "2016-06-24" @default.
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• W2063889189 date "2007-01-01" @default.
• W2063889189 modified "2023-10-14" @default.
• W2063889189 title "From dihydroxypyrimidine carboxylic acids to carboxamide HIV-1 integrase inhibitors: SAR around the amide moiety" @default.
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• W2063889189 doi "https://doi.org/10.1016/j.bmcl.2006.10.054" @default.
• W2063889189 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17107799" @default.
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