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- W2063891798 abstract "Erectile dysfunction (ED) may be the early clinical manifestation of a generalized vascular disease and carries an independent risk for cardiovascular events. Low-grade subclinical inflammation affects endothelial function and is involved in all stages of the atherosclerotic process. This review identifies potential pathophysiologic links among low-grade inflammation, ED, metabolic syndrome, and coronary artery disease (CAD) and presents the clinical implications in terms of ED diagnosis, assessment of patient risk, and therapy.A comprehensive evaluation was performed for available published data in full-length papers that were identified in MedLine up to July 2007.Studies support an association between metabolic syndrome, ED, and increased inflammatory state. Increased circulating levels of inflammatory and endothelial-prothrombotic compounds are related to the presence and severity of ED. Specific inflammatory biomarkers and their combination appear to have the potential to aid ED diagnosis or exclusion. ED and CAD may confer a similar unfavorable impact on the inflammatory and prothrombotic state, whereas ED adds an incremental activation on top of CAD; these findings have important implications for cardiovascular risk. Lifestyle and risk factor modification, as well as pharmacologic therapy, are associated with anti-inflammatory effects.Low-grade systemic inflammation could be an important element of the association between metabolic syndrome, ED, and CAD. Its individualized assessment may be a valuable tool for ED diagnosis, risk assessment, and rationalized therapeutic approach especially in patients with ED who have metabolic syndrome and carry an intermediate risk for future cardiovascular events." @default.
- W2063891798 created "2016-06-24" @default.
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- W2063891798 date "2007-12-01" @default.
- W2063891798 modified "2023-10-13" @default.
- W2063891798 title "Inflammation, Metabolic Syndrome, Erectile Dysfunction, and Coronary Artery Disease: Common Links" @default.
- W2063891798 cites W1577498128 @default.
- W2063891798 cites W1963798910 @default.
- W2063891798 cites W1964943029 @default.
- W2063891798 cites W1967789824 @default.
- W2063891798 cites W1970513210 @default.
- W2063891798 cites W1975582897 @default.
- W2063891798 cites W1977678369 @default.
- W2063891798 cites W1978449362 @default.
- W2063891798 cites W1980732197 @default.
- W2063891798 cites W1981752991 @default.
- W2063891798 cites W1984533748 @default.
- W2063891798 cites W1984618245 @default.
- W2063891798 cites W1989187668 @default.
- W2063891798 cites W1994104408 @default.
- W2063891798 cites W2002230059 @default.
- W2063891798 cites W2007143735 @default.
- W2063891798 cites W2009051902 @default.
- W2063891798 cites W2013595930 @default.
- W2063891798 cites W2014619641 @default.
- W2063891798 cites W2015126772 @default.
- W2063891798 cites W2016312408 @default.
- W2063891798 cites W2019400394 @default.
- W2063891798 cites W2022209234 @default.
- W2063891798 cites W2031626173 @default.
- W2063891798 cites W2035067297 @default.
- W2063891798 cites W2037957754 @default.
- W2063891798 cites W2040141893 @default.
- W2063891798 cites W2041504274 @default.
- W2063891798 cites W2045650855 @default.
- W2063891798 cites W2045719262 @default.
- W2063891798 cites W2048438995 @default.
- W2063891798 cites W2059350161 @default.
- W2063891798 cites W2059794066 @default.
- W2063891798 cites W2060412109 @default.
- W2063891798 cites W2060514802 @default.
- W2063891798 cites W2061962106 @default.
- W2063891798 cites W2063316820 @default.
- W2063891798 cites W2064475494 @default.
- W2063891798 cites W2068218731 @default.
- W2063891798 cites W2069754225 @default.
- W2063891798 cites W2072376419 @default.
- W2063891798 cites W2078640748 @default.
- W2063891798 cites W2080054477 @default.
- W2063891798 cites W2083336004 @default.
- W2063891798 cites W2086415913 @default.
- W2063891798 cites W2094576470 @default.
- W2063891798 cites W2094968080 @default.
- W2063891798 cites W2097424152 @default.
- W2063891798 cites W2100904403 @default.
- W2063891798 cites W2103760597 @default.
- W2063891798 cites W2109156184 @default.
- W2063891798 cites W2110109612 @default.
- W2063891798 cites W2111494287 @default.
- W2063891798 cites W2111745105 @default.
- W2063891798 cites W2114542908 @default.
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- W2063891798 cites W2126556811 @default.
- W2063891798 cites W2129226078 @default.
- W2063891798 cites W2138753856 @default.
- W2063891798 cites W2138798974 @default.
- W2063891798 cites W2142248791 @default.
- W2063891798 cites W2143921624 @default.
- W2063891798 cites W2149263243 @default.
- W2063891798 cites W2157053766 @default.
- W2063891798 cites W2158368439 @default.
- W2063891798 cites W2159087408 @default.
- W2063891798 cites W2159818171 @default.
- W2063891798 cites W2161350787 @default.
- W2063891798 cites W2161577433 @default.
- W2063891798 cites W2165533293 @default.
- W2063891798 cites W2168643678 @default.
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- W2063891798 doi "https://doi.org/10.1016/j.eururo.2007.08.004" @default.
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- W2063891798 hasPublicationYear "2007" @default.
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