FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2063925605> ?p ?o ?g. }

• W2063925605 endingPage "57" @default.
• W2063925605 startingPage "47" @default.
• W2063925605 abstract "Abstract Pregabalin is a commonly used therapy currently recommended as first‐line treatment for a number of neuropathic pain (NeP) conditions. Since licensure, a number of clinical trials of pregabalin in different NeP conditions have been completed from which additional data on safety and tolerability can be drawn. In this analysis, patient‐level data from 31 randomized clinical trials of pregabalin in peripheral NeP sponsored by Pfizer were pooled and assessed for incidence of adverse events ( AE s). Incidence by age, disease condition, and race, together with risk differences and time to onset and resolution of AE s, was assessed. In total, 7,510 patients were included: 4,884 on pregabalin (representing 805 patient‐years treatment) and 2,626 on placebo. Pregabalin vs. placebo risk analysis identified 9 AE s with a risk difference, for which the lower limit of the 95% confidence interval ( CI ) was > 1%: dizziness (risk difference [95% CI ]: (17.0 [15.4 to 18.6]), somnolence (10.8 [9.5 to 12.1]), peripheral edema (5.4 [4.3 to 6.4]), weight increase (4.7 [3.9 to 5.5]), dry mouth (2.9 [2.1 to 3.8]), constipation (2.3 [1.5 to 3.2]), blurred vision (2.2 [1.6 to 2.9]), balance disorder (2.0 [1.5 to 2.5]), and euphoric mood (1.6 [1.2 to 2.0]). The most common AE s, dizziness and somnolence, typically emerged within the first 1 to 2 weeks of treatment and resolved 1 to 2 weeks later, without resulting in cessation of treatment. The data from this review provide information, indicating which AE s may be expected in patients treated with pregabalin, and suggest that careful dose titration to the highest tolerable dose is the most appropriate approach in clinical practice." @default.
• W2063925605 created "2016-06-24" @default.
• W2063925605 creator A5020043337 @default.
• W2063925605 creator A5021885089 @default.
• W2063925605 creator A5023557130 @default.
• W2063925605 creator A5031987528 @default.
• W2063925605 creator A5042073172 @default.
• W2063925605 creator A5046115676 @default.
• W2063925605 creator A5077852771 @default.
• W2063925605 date "2013-11-27" @default.
• W2063925605 modified "2023-10-03" @default.
• W2063925605 title "A Comprehensive Drug Safety Evaluation of Pregabalin in Peripheral Neuropathic Pain" @default.
• W2063925605 cites W1476661220 @default.
• W2063925605 cites W1845521331 @default.
• W2063925605 cites W1965579959 @default.
• W2063925605 cites W1970505244 @default.
• W2063925605 cites W1972387365 @default.
• W2063925605 cites W1978614429 @default.
• W2063925605 cites W1991677473 @default.
• W2063925605 cites W1996761484 @default.
• W2063925605 cites W2001322197 @default.
• W2063925605 cites W2007225730 @default.
• W2063925605 cites W2011913908 @default.
• W2063925605 cites W2016474170 @default.
• W2063925605 cites W2020407769 @default.
• W2063925605 cites W2024292114 @default.
• W2063925605 cites W2040110933 @default.
• W2063925605 cites W2049689960 @default.
• W2063925605 cites W2050386055 @default.
• W2063925605 cites W2053149411 @default.
• W2063925605 cites W2054260401 @default.
• W2063925605 cites W2058596886 @default.
• W2063925605 cites W2061126722 @default.
• W2063925605 cites W2065199904 @default.
• W2063925605 cites W2068602147 @default.
• W2063925605 cites W2068757724 @default.
• W2063925605 cites W2070246197 @default.
• W2063925605 cites W2070651571 @default.
• W2063925605 cites W2076716839 @default.
• W2063925605 cites W2082846225 @default.
• W2063925605 cites W2084567915 @default.
• W2063925605 cites W2090637590 @default.
• W2063925605 cites W2092918915 @default.
• W2063925605 cites W2094822188 @default.
• W2063925605 cites W2099304023 @default.
• W2063925605 cites W2105781860 @default.
• W2063925605 cites W2112690253 @default.
• W2063925605 cites W2115451671 @default.
• W2063925605 cites W2117568115 @default.
• W2063925605 cites W2119752070 @default.
• W2063925605 cites W2119931634 @default.
• W2063925605 cites W2120306614 @default.
• W2063925605 cites W2125761169 @default.
• W2063925605 cites W2128412489 @default.
• W2063925605 cites W2136415182 @default.
• W2063925605 cites W2139432419 @default.
• W2063925605 cites W2158523533 @default.
• W2063925605 cites W2159977024 @default.
• W2063925605 cites W2399662290 @default.
• W2063925605 cites W2502244659 @default.
• W2063925605 doi "https://doi.org/10.1111/papr.12146" @default.
• W2063925605 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4320770" @default.
• W2063925605 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24279736" @default.
• W2063925605 hasPublicationYear "2013" @default.
• W2063925605 type Work @default.
• W2063925605 sameAs 2063925605 @default.
• W2063925605 citedByCount "57" @default.
• W2063925605 countsByYear W20639256052014 @default.
• W2063925605 countsByYear W20639256052015 @default.
• W2063925605 countsByYear W20639256052016 @default.
• W2063925605 countsByYear W20639256052017 @default.
• W2063925605 countsByYear W20639256052018 @default.
• W2063925605 countsByYear W20639256052019 @default.
• W2063925605 countsByYear W20639256052020 @default.
• W2063925605 countsByYear W20639256052021 @default.
• W2063925605 countsByYear W20639256052022 @default.
• W2063925605 countsByYear W20639256052023 @default.
• W2063925605 crossrefType "journal-article" @default.
• W2063925605 hasAuthorship W2063925605A5020043337 @default.
• W2063925605 hasAuthorship W2063925605A5021885089 @default.
• W2063925605 hasAuthorship W2063925605A5023557130 @default.
• W2063925605 hasAuthorship W2063925605A5031987528 @default.
• W2063925605 hasAuthorship W2063925605A5042073172 @default.
• W2063925605 hasAuthorship W2063925605A5046115676 @default.
• W2063925605 hasAuthorship W2063925605A5077852771 @default.
• W2063925605 hasBestOaLocation W20639256051 @default.
• W2063925605 hasConcept C126322002 @default.
• W2063925605 hasConcept C142724271 @default.
• W2063925605 hasConcept C197934379 @default.
• W2063925605 hasConcept C204787440 @default.
• W2063925605 hasConcept C27081682 @default.
• W2063925605 hasConcept C2776468701 @default.
• W2063925605 hasConcept C2777107010 @default.
• W2063925605 hasConcept C2777482430 @default.
• W2063925605 hasConcept C2778375690 @default.
• W2063925605 hasConcept C2779034229 @default.
• W2063925605 hasConcept C42219234 @default.
• W2063925605 hasConcept C71924100 @default.

• next