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- W2063939791 abstract "The immunomodulatory properties of botanical medicinals are well-documented. In this study, the capacity for the traditional Chinese herbal medicine, Rehmannia Six Formula (R6F), to stimulate anti-tetanus toxoid (TT) immunity following oral administration to mice was examined. A significant rise in serum anti-TT antibody levels were observed in R6F-treated mice immunized with a minimum immunogenic dose of 10 microg TT suggesting an oral adjuvant effect. No such enhancement was found for unimmunized mice treated with R6F. This anti-TT response was preferentially IgG and antigen-specific in relation to antibody reactivity to a panel of unrelated antigens. The R6F used was safe with no adverse effects on mouse weight or survival, providing evidence for the use of R6F as an oral adjuvant." @default.
- W2063939791 created "2016-06-24" @default.
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- W2063939791 creator A5018832748 @default.
- W2063939791 creator A5042946035 @default.
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- W2063939791 date "2009-11-01" @default.
- W2063939791 modified "2023-10-16" @default.
- W2063939791 title "Stimulation of tetanus toxoid-specific immune responses by a traditional Chinese herbal medicine" @default.
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- W2063939791 doi "https://doi.org/10.1016/j.vaccine.2009.03.051" @default.
- W2063939791 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19781825" @default.
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