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- W2063971838 endingPage "2023" @default.
- W2063971838 startingPage "2014" @default.
- W2063971838 abstract "Early embryo loss is a key factor affecting fertility in dairy and beef herds. Prior to implantation, the bovine embryo spends around 16 days free-floating in the uterine environment and is dependent on the composition of uterine fluid for normal growth and development. However, there is a lack of information regarding the protein composition of the bovine uterus and how it relates to plasma. In this study, uterine flushings (UF) (n = 6) and blood plasma (n = 4) were collected from beef heifers on day 7 of the oestrous cycle, albumin depleted and compared using iTRAQ proteomics. A total of 35 proteins were higher and 18 were lower in UF including metabolic enzymes, proteins with anti-oxidant activity and those involved in modulation of the immune response. This study confirms the dynamic nature of the bovine uterine proteome and that it differs from plasma. Factors affecting the uterine proteome and how it impacts on embryo survival warrant further study." @default.
- W2063971838 created "2016-06-24" @default.
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- W2063971838 creator A5065092823 @default.
- W2063971838 creator A5067565306 @default.
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- W2063971838 date "2012-06-01" @default.
- W2063971838 modified "2023-09-30" @default.
- W2063971838 title "A comparison of the bovine uterine and plasma proteome using iTRAQ proteomics" @default.
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- W2063971838 doi "https://doi.org/10.1002/pmic.201100609" @default.
- W2063971838 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22623423" @default.
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