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• W2063996475 abstract "Within optogenetics there is a need for compact light sources that are capable of delivering light with excellent spatial, temporal, and spectral resolution to deep brain structures. Here, we demonstrate a custom GaN-based LED probe for such applications and the electrical, optical, and thermal properties are analyzed. The output power density and emission spectrum were found to be suitable for stimulating channelrhodopsin-2, one of the most common light-sensitive proteins currently used in optogenetics. The LED device produced high light intensities, far in excess of those required to stimulate the light-sensitive proteins within the neurons. Thermal performance was also investigated, illustrating that a broad range of operating regimes in pulsed mode are accessible while keeping a minimum increase in temperature for the brain (0.5&#xB0;C). This type of custom device represents a significant step forward for the optogenetics community, allowing multiple bright excitation sites along the length of a minimally invasive neural probe." @default.
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• W2063996475 date "2013-03-15" @default.
• W2063996475 modified "2023-10-16" @default.
• W2063996475 title "Thermal and optical characterization of micro-LED probes for in vivo optogenetic neural stimulation" @default.
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• W2063996475 doi "https://doi.org/10.1364/ol.38.000992" @default.
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