FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2063997180> ?p ?o ?g. }

• W2063997180 endingPage "350" @default.
• W2063997180 startingPage "350" @default.
• W2063997180 abstract "Adipose tissue produces adipocytokines of uncertain clinical significance.We analyzed the relationships among adiposity, adipocytokines, glycemia, and incident diabetes mellitus in 2356 white and black adults aged 70 to 79 years in the Health, Aging, and Body Composition Study who did not have diabetes at baseline. We measured the levels of adipocytokines adiponectin, leptin, interleukin 6, tumor necrosis factor alpha, and plasminogen activator inhibitor 1. Regional fat area was determined by means of computed tomography. New diabetes was defined as a self-reported diagnosis of diabetes or as a fasting plasma glucose level of 126 mg/dL or greater (>/=7.0 mmol/L) at the second, fourth, or sixth annual examination.A total of 143 participants (14.1 cases per 1000 person-years) developed diabetes across 5 years. Visceral fat area (odds ratio [OR], 1.33; 95% confidence interval [CI], 1.10-1.60 per standard deviation increase) and body mass index (white individuals: OR, 1.65; 95% CI, 1.26-2.15 per standard deviation increase; black individuals: OR, 1.22; 95% CI, 0.99-1.51 per standard deviation increase) independently predicted incident diabetes. Adiponectin, leptin, and plasminogen activator inhibitor 1 attenuated the relationship between adiposity and diabetes. After controlling for body mass index, visceral fat, fasting glucose, fasting insulin, high-density lipoprotein cholesterol, triglycerides, and hypertension at baseline, plasminogen activator inhibitor 1 was the only adipocytokine independently associated with increased odds of diabetes (OR, 1.35; 95% CI, 1.01-1.81). Fasting glucose level at baseline remained a strong predictor of incident diabetes, whereas associations with body mass index and visceral fat were attenuated.Adipocytokines and glycemia partially account for the relationship between adiposity and risk of type 2 diabetes due to adiposity. Plasminogen activator inhibitor 1 may be a useful predictor of diabetes in addition to measurements of body fat." @default.
• W2063997180 created "2016-06-24" @default.
• W2063997180 creator A5004078350 @default.
• W2063997180 creator A5018378907 @default.
• W2063997180 creator A5024607078 @default.
• W2063997180 creator A5027831105 @default.
• W2063997180 creator A5036496822 @default.
• W2063997180 creator A5040530822 @default.
• W2063997180 creator A5044875947 @default.
• W2063997180 creator A5069121445 @default.
• W2063997180 date "2006-02-13" @default.
• W2063997180 modified "2023-09-28" @default.
• W2063997180 title "Adipocytokines and Incident Diabetes Mellitus in Older Adults" @default.
• W2063997180 cites W110910239 @default.
• W2063997180 cites W1525234895 @default.
• W2063997180 cites W1590967073 @default.
• W2063997180 cites W178954517 @default.
• W2063997180 cites W1965968684 @default.
• W2063997180 cites W1979286266 @default.
• W2063997180 cites W1990440458 @default.
• W2063997180 cites W1990923058 @default.
• W2063997180 cites W2010374889 @default.
• W2063997180 cites W2016560465 @default.
• W2063997180 cites W2018135697 @default.
• W2063997180 cites W2025062210 @default.
• W2063997180 cites W2035498702 @default.
• W2063997180 cites W2060256649 @default.
• W2063997180 cites W2061694846 @default.
• W2063997180 cites W2062478697 @default.
• W2063997180 cites W2073637312 @default.
• W2063997180 cites W2076706839 @default.
• W2063997180 cites W2078489282 @default.
• W2063997180 cites W2085194341 @default.
• W2063997180 cites W2094595851 @default.
• W2063997180 cites W2099521374 @default.
• W2063997180 cites W2104858407 @default.
• W2063997180 cites W2105641300 @default.
• W2063997180 cites W2106523304 @default.
• W2063997180 cites W2123009561 @default.
• W2063997180 cites W2125407302 @default.
• W2063997180 cites W2126718674 @default.
• W2063997180 cites W2127187614 @default.
• W2063997180 cites W2128846862 @default.
• W2063997180 cites W2130680018 @default.
• W2063997180 cites W2130684278 @default.
• W2063997180 cites W2131363228 @default.
• W2063997180 cites W2132594773 @default.
• W2063997180 cites W2132681327 @default.
• W2063997180 cites W2134922435 @default.
• W2063997180 cites W2135073334 @default.
• W2063997180 cites W2135298791 @default.
• W2063997180 cites W2135523822 @default.
• W2063997180 cites W2139203772 @default.
• W2063997180 cites W2140254580 @default.
• W2063997180 cites W2146302501 @default.
• W2063997180 cites W2146536851 @default.
• W2063997180 cites W2150532258 @default.
• W2063997180 cites W2151857895 @default.
• W2063997180 cites W2153214557 @default.
• W2063997180 cites W2153962063 @default.
• W2063997180 cites W2158822657 @default.
• W2063997180 cites W2161914374 @default.
• W2063997180 cites W2168761911 @default.
• W2063997180 cites W2329569921 @default.
• W2063997180 cites W2332951586 @default.
• W2063997180 cites W2336672206 @default.
• W2063997180 cites W2398217550 @default.
• W2063997180 cites W2411826498 @default.
• W2063997180 cites W292647304 @default.
• W2063997180 doi "https://doi.org/10.1001/archinte.166.3.350" @default.
• W2063997180 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16476877" @default.
• W2063997180 hasPublicationYear "2006" @default.
• W2063997180 type Work @default.
• W2063997180 sameAs 2063997180 @default.
• W2063997180 citedByCount "86" @default.
• W2063997180 countsByYear W20639971802012 @default.
• W2063997180 countsByYear W20639971802013 @default.
• W2063997180 countsByYear W20639971802014 @default.
• W2063997180 countsByYear W20639971802015 @default.
• W2063997180 countsByYear W20639971802016 @default.
• W2063997180 countsByYear W20639971802017 @default.
• W2063997180 countsByYear W20639971802018 @default.
• W2063997180 countsByYear W20639971802020 @default.
• W2063997180 countsByYear W20639971802021 @default.
• W2063997180 countsByYear W20639971802022 @default.
• W2063997180 countsByYear W20639971802023 @default.
• W2063997180 crossrefType "journal-article" @default.
• W2063997180 hasAuthorship W2063997180A5004078350 @default.
• W2063997180 hasAuthorship W2063997180A5018378907 @default.
• W2063997180 hasAuthorship W2063997180A5024607078 @default.
• W2063997180 hasAuthorship W2063997180A5027831105 @default.
• W2063997180 hasAuthorship W2063997180A5036496822 @default.
• W2063997180 hasAuthorship W2063997180A5040530822 @default.
• W2063997180 hasAuthorship W2063997180A5044875947 @default.
• W2063997180 hasAuthorship W2063997180A5069121445 @default.
• W2063997180 hasBestOaLocation W20639971801 @default.
• W2063997180 hasConcept C126322002 @default.
• W2063997180 hasConcept C134018914 @default.

• next