FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2064040078> ?p ?o ?g. }

• W2064040078 endingPage "363" @default.
• W2064040078 startingPage "343" @default.
• W2064040078 abstract "Abstract The complementary consensus acceptor exon:intron junction d(ApCpCpTpGpTpApG) has been synthesized by a modified phosphotriester method. The non self-complementary octamer exists in the random coil form in aqueous buffer at 20°C as evidenced by temperature variable 1H-NMR and NOE measurements. The non-exchangeable proton assignments were secured using a combination of techniques including two-dimensional COSY, NOESY and 1H-1H-INADEQUATE. The octamer was annealed with the primary consensus sequence d(CpTpApCpApGpGpT). Confirmation of complete duplex formation was confirmed by detection and assignment of imino protons in D2O:H2O mixtures. Assignment of the nonexchangeable proton signals in the duplex consensus junction was then secured by a combination of two-dimensional COSY correlations, NOESY and NOE experiments. Determination of individual vicinal coupling constants in the component deoxyribose moieties permitted deduction of the population of S conformations in this sequence. It is concluded that the consensus acceptor junction exists in solution in a conformation belonging to the B family, and that the bases are oriented anti. In addition the deoxyribose moieties in the 5′ regions exist predominantly in the S form (2′endo—3′exo) whereas those residues on or adjacent to the junction on the primary strand show more N character (2′exo—3′endo). The contiguous bases A5-G6 (adjacent to the junction) and A15-G16 are stacked more closely than the other neighbor bases in this duplex sequence. These subtle structural and conformational differences in the exon:intron junction may serve as recognition signals for these critical sites in the genome." @default.
• W2064040078 created "2016-06-24" @default.
• W2064040078 creator A5011803721 @default.
• W2064040078 creator A5032537525 @default.
• W2064040078 creator A5042803541 @default.
• W2064040078 creator A5090061858 @default.
• W2064040078 creator A5047028160 @default.
• W2064040078 date "1986-12-01" @default.
• W2064040078 modified "2023-09-25" @default.
• W2064040078 title "Structure and Conformation of the Duplex Consensus Acceptor Exon: Intron Junction d [(CpTpApCpApGpGpT) (ApCpCpTpGpTpApG)] deduced from High-Field1H-NMR of Non-Exchangeable and Imino Protons" @default.
• W2064040078 cites W1594551351 @default.
• W2064040078 cites W1965051773 @default.
• W2064040078 cites W1969909989 @default.
• W2064040078 cites W1975154393 @default.
• W2064040078 cites W1977728729 @default.
• W2064040078 cites W1978743038 @default.
• W2064040078 cites W1982610079 @default.
• W2064040078 cites W1994260783 @default.
• W2064040078 cites W2000323760 @default.
• W2064040078 cites W2002355363 @default.
• W2064040078 cites W2005451802 @default.
• W2064040078 cites W2006641720 @default.
• W2064040078 cites W2009103135 @default.
• W2064040078 cites W2010528272 @default.
• W2064040078 cites W2012911917 @default.
• W2064040078 cites W2021054898 @default.
• W2064040078 cites W2025854822 @default.
• W2064040078 cites W2047186674 @default.
• W2064040078 cites W2049031211 @default.
• W2064040078 cites W2055829158 @default.
• W2064040078 cites W2062375578 @default.
• W2064040078 cites W2073105366 @default.
• W2064040078 cites W2076720109 @default.
• W2064040078 cites W2080887557 @default.
• W2064040078 cites W2081351777 @default.
• W2064040078 cites W2086877747 @default.
• W2064040078 cites W2093393945 @default.
• W2064040078 cites W2094244490 @default.
• W2064040078 cites W2094944935 @default.
• W2064040078 cites W2103026185 @default.
• W2064040078 cites W2109473626 @default.
• W2064040078 cites W2112160477 @default.
• W2064040078 cites W2117255074 @default.
• W2064040078 cites W2124349385 @default.
• W2064040078 cites W2316945635 @default.
• W2064040078 cites W280694366 @default.
• W2064040078 cites W4252911439 @default.
• W2064040078 doi "https://doi.org/10.1080/07391102.1986.10506354" @default.
• W2064040078 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3271448" @default.
• W2064040078 hasPublicationYear "1986" @default.
• W2064040078 type Work @default.
• W2064040078 sameAs 2064040078 @default.
• W2064040078 citedByCount "16" @default.
• W2064040078 countsByYear W20640400782013 @default.
• W2064040078 countsByYear W20640400782014 @default.
• W2064040078 countsByYear W20640400782019 @default.
• W2064040078 crossrefType "journal-article" @default.
• W2064040078 hasAuthorship W2064040078A5011803721 @default.
• W2064040078 hasAuthorship W2064040078A5032537525 @default.
• W2064040078 hasAuthorship W2064040078A5042803541 @default.
• W2064040078 hasAuthorship W2064040078A5047028160 @default.
• W2064040078 hasAuthorship W2064040078A5090061858 @default.
• W2064040078 hasConcept C103319777 @default.
• W2064040078 hasConcept C121332964 @default.
• W2064040078 hasConcept C173681060 @default.
• W2064040078 hasConcept C178790620 @default.
• W2064040078 hasConcept C185592680 @default.
• W2064040078 hasConcept C19549132 @default.
• W2064040078 hasConcept C26873012 @default.
• W2064040078 hasConcept C2777709666 @default.
• W2064040078 hasConcept C2779892579 @default.
• W2064040078 hasConcept C33347731 @default.
• W2064040078 hasConcept C552990157 @default.
• W2064040078 hasConcept C55493867 @default.
• W2064040078 hasConcept C64927066 @default.
• W2064040078 hasConcept C66974803 @default.
• W2064040078 hasConcept C71240020 @default.
• W2064040078 hasConcept C8010536 @default.
• W2064040078 hasConcept C84772758 @default.
• W2064040078 hasConcept C99611785 @default.
• W2064040078 hasConceptScore W2064040078C103319777 @default.
• W2064040078 hasConceptScore W2064040078C121332964 @default.
• W2064040078 hasConceptScore W2064040078C173681060 @default.
• W2064040078 hasConceptScore W2064040078C178790620 @default.
• W2064040078 hasConceptScore W2064040078C185592680 @default.
• W2064040078 hasConceptScore W2064040078C19549132 @default.
• W2064040078 hasConceptScore W2064040078C26873012 @default.
• W2064040078 hasConceptScore W2064040078C2777709666 @default.
• W2064040078 hasConceptScore W2064040078C2779892579 @default.
• W2064040078 hasConceptScore W2064040078C33347731 @default.
• W2064040078 hasConceptScore W2064040078C552990157 @default.
• W2064040078 hasConceptScore W2064040078C55493867 @default.
• W2064040078 hasConceptScore W2064040078C64927066 @default.
• W2064040078 hasConceptScore W2064040078C66974803 @default.
• W2064040078 hasConceptScore W2064040078C71240020 @default.
• W2064040078 hasConceptScore W2064040078C8010536 @default.
• W2064040078 hasConceptScore W2064040078C84772758 @default.
• W2064040078 hasConceptScore W2064040078C99611785 @default.

• next