FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2064041669> ?p ?o ?g. }

• W2064041669 endingPage "514" @default.
• W2064041669 startingPage "505" @default.
• W2064041669 abstract "The purpose of this study was to compare the protection afforded by individualized doses of theophylline and a cromolyn metered-dose inhaler (MDI) during allergen challenge.The study design was randomized, double-blind, and crossover. Responses to inhaled allergen were measured in 16 subjects with allergic asthma (age range, 18 to 35 years) after 7 days of treatment with either placebo, once daily slow-release theophylline producing a mean +/- SD serum concentration of 16 +/- 5 micrograms/ml during the late phase, or 2 mg of cromolyn administered by MDI four times daily. Forced expiratory volume in 1 second was measured at frequent intervals, and airway responsiveness to histamine was measured before and 3 hours after allergen challenge.The mean +/- SD maximum decrease in forced expiratory volume in 1 second during the late phase was 30% +/- 14% during placebo treatment, 16% +/- 13% during theophylline treatment, and 13% +/- 14% during cromolyn treatment (placebo vs theophylline and cromolyn, p = 0.0001; theophylline vs cromolyn, p = 0.1). The geometric mean fold increase in airway responsiveness was 3.0 +/- 1.7 during placebo treatment, 1.7 +/- 1.7 during theophylline treatment, and 1.5 +/- 1.6 during cromolyn treatment (placebo vs theophylline and cromolyn, p = 0.0001; theophylline vs cromolyn, p = 0.1).Theophylline, when administered once daily as a slow-release formulation, was as effective as cromolyn, administered four times daily through an MDI, in attenuating airway responses to inhaled allergen. The protection afforded by both treatments, however, was modest when compared with the results of similar studies with inhaled corticosteroids or other cromolyn formulations that deliver more drug to the lungs than the MDI available in the United States." @default.
• W2064041669 created "2016-06-24" @default.
• W2064041669 creator A5035006177 @default.
• W2064041669 creator A5040408813 @default.
• W2064041669 creator A5043014729 @default.
• W2064041669 creator A5045090879 @default.
• W2064041669 creator A5063674308 @default.
• W2064041669 creator A5073215469 @default.
• W2064041669 date "1995-02-01" @default.
• W2064041669 modified "2023-10-18" @default.
• W2064041669 title "Theophylline attenuation of airway responses to allergen: Comparison with cromolyn metered-dose inhaler" @default.
• W2064041669 cites W1513487015 @default.
• W2064041669 cites W1972111664 @default.
• W2064041669 cites W2000094398 @default.
• W2064041669 cites W2000470005 @default.
• W2064041669 cites W2003070392 @default.
• W2064041669 cites W2009176876 @default.
• W2064041669 cites W2018958630 @default.
• W2064041669 cites W2023426963 @default.
• W2064041669 cites W2039142516 @default.
• W2064041669 cites W2040669647 @default.
• W2064041669 cites W2045997031 @default.
• W2064041669 cites W2050174218 @default.
• W2064041669 cites W2051168907 @default.
• W2064041669 cites W2052225778 @default.
• W2064041669 cites W2052683492 @default.
• W2064041669 cites W2060553555 @default.
• W2064041669 cites W2070078780 @default.
• W2064041669 cites W2086689700 @default.
• W2064041669 cites W2087608722 @default.
• W2064041669 cites W2088700715 @default.
• W2064041669 cites W2094440568 @default.
• W2064041669 cites W2094586942 @default.
• W2064041669 cites W2102617857 @default.
• W2064041669 cites W2107348065 @default.
• W2064041669 cites W2130055066 @default.
• W2064041669 cites W2151665493 @default.
• W2064041669 cites W2157891740 @default.
• W2064041669 cites W2169146034 @default.
• W2064041669 cites W4249821670 @default.
• W2064041669 cites W4368235451 @default.
• W2064041669 doi "https://doi.org/10.1016/s0091-6749(95)70312-8" @default.
• W2064041669 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7852666" @default.
• W2064041669 hasPublicationYear "1995" @default.
• W2064041669 type Work @default.
• W2064041669 sameAs 2064041669 @default.
• W2064041669 citedByCount "39" @default.
• W2064041669 countsByYear W20640416692014 @default.
• W2064041669 countsByYear W20640416692016 @default.
• W2064041669 countsByYear W20640416692018 @default.
• W2064041669 crossrefType "journal-article" @default.
• W2064041669 hasAuthorship W2064041669A5035006177 @default.
• W2064041669 hasAuthorship W2064041669A5040408813 @default.
• W2064041669 hasAuthorship W2064041669A5043014729 @default.
• W2064041669 hasAuthorship W2064041669A5045090879 @default.
• W2064041669 hasAuthorship W2064041669A5063674308 @default.
• W2064041669 hasAuthorship W2064041669A5073215469 @default.
• W2064041669 hasConcept C126322002 @default.
• W2064041669 hasConcept C142724271 @default.
• W2064041669 hasConcept C203014093 @default.
• W2064041669 hasConcept C204787440 @default.
• W2064041669 hasConcept C207480886 @default.
• W2064041669 hasConcept C27081682 @default.
• W2064041669 hasConcept C2776042228 @default.
• W2064041669 hasConcept C2778095195 @default.
• W2064041669 hasConcept C2780261241 @default.
• W2064041669 hasConcept C2780510475 @default.
• W2064041669 hasConcept C2780667556 @default.
• W2064041669 hasConcept C2781018748 @default.
• W2064041669 hasConcept C2911192292 @default.
• W2064041669 hasConcept C42219234 @default.
• W2064041669 hasConcept C71924100 @default.
• W2064041669 hasConcept C87813604 @default.
• W2064041669 hasConcept C98274493 @default.
• W2064041669 hasConceptScore W2064041669C126322002 @default.
• W2064041669 hasConceptScore W2064041669C142724271 @default.
• W2064041669 hasConceptScore W2064041669C203014093 @default.
• W2064041669 hasConceptScore W2064041669C204787440 @default.
• W2064041669 hasConceptScore W2064041669C207480886 @default.
• W2064041669 hasConceptScore W2064041669C27081682 @default.
• W2064041669 hasConceptScore W2064041669C2776042228 @default.
• W2064041669 hasConceptScore W2064041669C2778095195 @default.
• W2064041669 hasConceptScore W2064041669C2780261241 @default.
• W2064041669 hasConceptScore W2064041669C2780510475 @default.
• W2064041669 hasConceptScore W2064041669C2780667556 @default.
• W2064041669 hasConceptScore W2064041669C2781018748 @default.
• W2064041669 hasConceptScore W2064041669C2911192292 @default.
• W2064041669 hasConceptScore W2064041669C42219234 @default.
• W2064041669 hasConceptScore W2064041669C71924100 @default.
• W2064041669 hasConceptScore W2064041669C87813604 @default.
• W2064041669 hasConceptScore W2064041669C98274493 @default.
• W2064041669 hasIssue "2" @default.
• W2064041669 hasLocation W20640416691 @default.
• W2064041669 hasLocation W20640416692 @default.
• W2064041669 hasOpenAccess W2064041669 @default.
• W2064041669 hasPrimaryLocation W20640416691 @default.
• W2064041669 hasRelatedWork W2009699472 @default.
• W2064041669 hasRelatedWork W2018997574 @default.

• next